Establishment and Development of Quality Evaluation Method for Sangbaipi Decoction ,,,and.,Journal of AOAC INTERNATIONAL

当前位置： X-MOL 学术 › J. AOAC Int. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Establishment and Development of Quality Evaluation Method for Sangbaipi Decoction ,,,and.
Journal of AOAC INTERNATIONAL ( IF 1.6 ) Pub Date : 2021-04-28 , DOI: 10.1093/jaoacint/qsab065
Huiwei Bao ₁ , Huailei Yang ₂ , Jize Li ₁ , Yang Xu _{3,

4} , Xiaowei Huang ₁

Affiliation

BACKGROUND Sangbaipi Decoction(SD), a traditional Chinese "Ancient Classical Prescriptions" consisting of eight medicinal materials, is usually used for asthma due to excess lung Qi and excessive phlegm-fire. OBJECTIVE To establish a comprehensive quality evaluation methods of SD. MATERIALS AND METHODS High performance liquid chromatography (HPLC) fingerprint analysis, hierarchical cluster analysis (HCA) and principal component analysis (PCA) were applied for quality control of SD prepared by different batches of medicinal materials. Subsequently, total 10 batches of SD samples were prepared and analyzed. RESULTS Total 24 common peaks and six peaks(gardenoside, rutin, berberine, palmatine, baicalein, and wogonin) were displayed and identified in HPLC fingerprint of SD. Ten batches of SD samples were divided into four groups via cluster analysis and principal component analysis. HPLC fingerprint similarities of 10 batches samples were not less than 0.934. The precision, stability, repeatability, and other methodological studies suggested that developed method met the requirements of qualitative research of fingerprint technology. CONCLUSION The result indicated that HPLC fingerprint combined with principal component analysis and multi-component determination can be successfully applied to the quality control of SD. This study can provide a basis for a more comprehensive quality evaluation method for SD as well.

更新日期：2021-04-28

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>