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Outcome of a HIV Positive Patient Infected with COVID-19 After an Autologous Bone Marrow Transplantation: A Case Report
Current HIV Research ( IF 1 ) Pub Date : 2021-06-30 , DOI: 10.2174/1570162x19666210423124839
Masoud Mardani 1 , Athena Sharifi-Razavi 2 , Shirin Sheibani 3 , Mana Baziboroun 1
Affiliation  

Background: The World Health Organization (WHO) announced the SARS-COV-2 disease pandemic on March 9, 2020. With the advent of this disease, another health burden was added to about 37.9 million people in the world who are infected with HIV and are suffering from various diseases. These people may be at serious risk of COVID-19. Information about the effects of COVID-19 on people living with HIV, is limited.

Case Presentation: We reported a 61-year-old man who was a known case of HIV from 6 years ago that was being treated with HAART (highly active antiretroviral therapy). He also had a history of Hodgkin’s lymphoma from 4 years ago who underwent autologous bone marrow transplantation (BMT) 2 weeks before given referral to our hospital. He complained of weakness, anorexia, and fever. RT-PCR for SARS-COV-2-RNA was positive in his nasopharyngeal and oropharyngeal swab. He was diagnosed with COVID-19 infection and treated with atazanavir. After one week, the patient discharged in a good general state.

Conclusion: To the best of our knowledge, it is the first report of COVID-19 infection in an HIV positive patient after BMT in Iran. Despite his immunodeficiency, COVID-19 disease had mild manifestations and he had a good prognosis. We hope that our report and that of others can remain promising to doctors and HIV patients cross fingers for COVID-19 recovery.



中文翻译:

自体骨髓移植后感染 COVID-19 的 HIV 阳性患者的结果:病例报告

背景:世界卫生组织 (WHO) 于 2020 年 3 月 9 日宣布了 SARS-COV-2 疾病大流行。随着该疾病的出现,全球约 3790 万感染 HIV 和正在患各种疾病。这些人可能有感染 COVID-19 的严重风险。关于 COVID-19 对 HIV 感染者的影响的信息有限。

病例介绍:我们报告了一名 61 岁男性,他是 6 年前已知的 HIV 病例,正在接受 HAART(高效抗逆转录病毒疗法)治疗。他还有 4 年前的霍奇金淋巴瘤病史,在转诊到我院前 2 周接受了自体骨髓移植 (BMT)。他抱怨虚弱、厌食和发烧。SARS-COV-2-RNA 的 RT-PCR 在他的鼻咽和口咽拭子中呈阳性。他被诊断出感染了 COVID-19,并接受了阿扎那韦治疗。一周后,患者出院,一般情况良好。

结论:据我们所知,这是伊朗首例 BMT 后 HIV 阳性患者感染 COVID-19 的报告。尽管他有免疫缺陷,但 COVID-19 病的表现较轻,预后良好。我们希望我们的报告和其他人的报告能够继续向医生和 HIV 患者祈祷 COVID-19 康复。

更新日期:2021-08-30
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