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Influence of anthopometric variables on the mechanical properties of human rib cortical bone
Biomedical Physics & Engineering Express Pub Date : 2021-04-26 , DOI: 10.1088/2057-1976/abf787
Juan Velázquez-Ameijide 1 , Silvia García-Vilana 1 , David Sánchez-Molina 1 , Eva Martínez-González 1 , Jordi Llumà 2 , M Carmen Rebollo-Soria 3 , Carlos Arregui-Dalmases 4
Affiliation  

Objective. The mechanical properties of ribs from a large number of post-mortem human subjects (PMHS) were analyzed to search for variation according to age, sex or BMI in the sample. A large sample of specimens from different donors (N = 64) with a very wide range of ages and anthropometric characteristics was tested. Methods. Uniaxial tensile tests were used for a sample of coupons machined from cortical bone tissue in order to isolate the purely mechanical properties from the geometrically influenced properties of the rib. Each coupon is about 25 mm long and has a thickness of about 0.5 mm. The mechanical properties measured for each specimen/coupon include YM, yield stress, ultimate stress (maximum failure stress), ultimate strain, and resilience (energy to fracture of SED). The study provides new methodological improvements in DIC techniques. Results. This study is notable for using an atypically large sample of number of PMHS. The size of the sample allowed the authors to determine that age has a significant effect on failure stress (p < 0.0001), yield stress (p = 0.0047), ultimate strain (p < 0.0001) and resilience (p < 0.0001) [numbers in parentheses represent the corresponding p − values]. Finally, there is a combined effect, so that for a given age, an increase of BMI leads to a decrease of the maximum strain (i.e. cortical bone is less stiff when both age and BMI are higher).



中文翻译:

人体测量变量对人体肋骨皮质骨力学性能的影响

客观。分析了来自大量死后人类受试者 (PMHS) 的肋骨的机械性能,以根据样本中的年龄、性别或 BMI 寻找变化。测试了来自不同捐赠者( N = 64)的大量样本,这些样本具有非常广泛的年龄和人体测量特征。方法. 单轴拉伸试验用于从皮质骨组织加工的试样样品,以便将纯机械性能与肋骨的几何影响性能隔离开来。每个试样长约 25 毫米,厚度约 0.5 毫米。为每个试样/试样测量的机械性能包括 YM、屈服应力、极限应力(最大破坏应力)、极限应变和弹性(SED 的断裂能量)。该研究为 DIC 技术提供了新的方法学改进。结果。这项研究值得注意的是使用了非典型的大量 PMHS 样本。样本的大小使作者能够确定年龄对失效应力 ( p < 0.0001)、屈服应力 ( p= 0.0047)、极限应变 ( p < 0.0001) 和弹性 ( p < 0.0001) [括号中的数字代表相应的p - 值]。最后,还有一个综合效应,因此对于给定的年龄,BMI 的增加会导致最大应变的降低(即,当年龄和 BMI 都较高时,皮质骨的硬度较低)。

更新日期:2021-04-26
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