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New Contemplation Upon Subjective Memory Complaints as a Self- Report Criterion for MCI Diagnosis
Current Alzheimer Research ( IF 2.1 ) Pub Date : 2021-01-31 , DOI: 10.2174/1567205018666210416095437
Merav Papirovitz 1 , Ariela Gigi 1
Affiliation  

Background: Subjective memory complaints are a key component in mild cognitive impairment (MCI) diagnosis. However, studies that examined memory awareness among MCI participants have published contradictory results. One possible explanation for the inconsistent findings could be the disregard from the multidimensional structure of subjective memory.

Objectives: The present study is directed at assessing subjective memory among healthy and MCI participants, referring to three main types of memory: episodic, semantic, and working memory.

Methods: Participants were 123 adults (aged 50-90). They were divided into two groups, the MCI group, and the control group, according to their objective cognitive performance in RAVL or Mo- CA tests. All participants filled a subjective memory questionnaire, assessing their awareness of episodic, semantic, and working memory.

Results: MCI participants estimated their semantic memory as significantly lower in comparison to the estimation of the healthy controls. By contrast, MCI participants showed an overestimation of their episodic memory capabilities compared to the control group. No significant difference was found between groups (MCI and healthy controls) in evaluating their working memory. In addition, for both groups, Pearson’s correlation revealed a significant negative correlation between age and semantic memory evaluation. Such correlation was not found for subjective episodic memory.

Discussion: Findings suggest that while people with MCI exhibit poor awareness of their episodic and working memory capabilities, their awareness of their decrease in semantic memory is apparently intact. Therefore, it is suggested that when using the self-report criterion for MCI diagnosis, clinicians should consider the patient’s’ semantic memory complaints.



中文翻译:

主观记忆抱怨作为 MCI 诊断的自我报告标准的新思考

背景:主观记忆主诉是轻度认知障碍 (MCI) 诊断的关键组成部分。然而,研究 MCI 参与者的记忆意识的研究发表了相互矛盾的结果。不一致的发现的一种可能解释可能是对主观记忆的多维结构的忽视。

目标:本研究旨在评估健康和 MCI 参与者的主观记忆,涉及三种主要类型的记忆:情景记忆、语义记忆和工作记忆。

方法:参与者为 123 名成年人(50-90 岁)。根据他们在 RAVL 或 Mo-CA 测试中的客观认知表现,将他们分为两组,MCI 组和对照组。所有参与者填写主观记忆问卷,评估他们对情节、语义和工作记忆的认识。

结果:与健康对照的估计相比,MCI 参与者估计他们的语义记忆显着降低。相比之下,与对照组相比,MCI 参与者表现出对情景记忆能力的高估。两组(MCI 和健康对照组)在评估工作记忆方面没有发现显着差异。此外,对于两组,Pearson 相关性揭示了年龄与语义记忆评估之间的显着负相关。主观情景记忆没有发现这种相关性。

讨论:研究结果表明,虽然患有 MCI 的人对其情景和工作记忆能力的认识很差,但他们对语义记忆减少的认识显然完好无损。因此,建议临床医生在使用自我报告标准进行MCI诊断时,应考虑患者的语义记忆主诉。

更新日期:2021-01-31
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