There is considerable interest in the development of hybrid organic-inorganic materials because of the potential for harvesting the unique capabilities that each system has to offer. Proteins are an especially attractive organic component owing to the high amount of chemical information encoded in their amino acid sequence, their amenability to molecular and computational (re)design, and the many structures and functions they specify. Genetic installation of solid-binding peptides (SBPs) within protein frameworks affords control over the position and orientation of adhesive and morphogenetic segments, and a path toward predictive synthesis and assembly of functional materials and devices, all while harnessing the built-in properties of the host scaffold. Here, we review the current understanding of the mechanisms through which SBPs bind to technologically relevant interfaces, with an emphasis on the variables that influence the process, and highlight the last decade of progress in the use of solid-binding proteins for hybrid and hierarchical materials synthesis. Expected final online publication date for the Annual Review of Chemical and Biomolecular Engineering, Volume 12 is June 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

中文翻译：

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固体结合蛋白：桥接合成，组装和在杂种和分级材料制造中的功能。

混合有机-无机材料的开发引起了极大的兴趣，因为它有可能收获每个系统必须提供的独特功能。蛋白质由于其氨基酸序列中编码的大量化学信息，对分子和计算（重新）设计的适应性以及它们指定的许多结构和功能，因此是特别有吸引力的有机成分。蛋白质框架内固相结合肽（SBP）的遗传安装可控制粘合剂和形态发生片段的位置和方向，并为功能材料和设备的预测性合成和组装提供一条途径，同时还能充分利用蛋白质的内在特性。宿主支架。这里，我们回顾了目前对SBP结合到技术上相关的界面的机制的理解，重点是影响过程的变量，并着重指出了使用固体结合蛋白进行杂化和分级材料合成的最近十年的进展。《化学和生物分子工程年度评论》第12卷的最终最终在线发布日期为2021年6月。有关修订的估算，请参见http://www.annualreviews.org/page/journal/pubdates。