OBJECTIVE To describe clinical features, diagnostic findings, treatments, and outcomes in patients with new-onset postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders following SARS-CoV-2 infection (COVID-19). METHODS We retrospectively reviewed medical records for patients who presented with persistent neurologic and cardiovascular complaints between April and December 2020 following COVID-19 infection. RESULTS Twenty patients (70% female) were included in this study.Fifteen had POTS, 3 had neurocardiogenic syncope, and 2 had orthostatic hypotension. Six patients had abnormalities on cardiac or pulmonary testing, and 4 had elevated autoimmune or inflammatory markers. All patients were treated with non-pharmacologic therapies, and most required pharmacologic therapies. Six to 8 months after COVID-19, 17 (85%) patients had residual autonomic symptoms, with 12 (60%) unable to return to work. CONCLUSIONS POTS can follow COVID-19 in previously healthy patients. Appropriate diagnostic investigations and therapies are necessary to identify and treat autonomic dysfunction after COVID-19.

中文翻译：

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COVID-19 感染后体位性直立性心动过速综合征 (POTS) 和其他自主神经紊乱：20 名患者的病例系列。

目的 描述 SARS-CoV-2 感染 (COVID-19) 后新发体位性直立性心动过速综合征 (POTS) 和其他自主神经障碍患者的临床特征、诊断结果、治疗和结果。方法 我们回顾性审查了 COVID-19 感染后在 2020 年 4 月至 2020 年 12 月期间出现持续神经系统和心血管疾病患者的医疗记录。结果 本研究共纳入 20 名患者（70% 为女性）。 15 名患有 POTS，3 名患有神经心源性晕厥，2 名患有直立性低血压。6 名患者的心脏或肺部检测异常，4 名患者自身免疫或炎症标志物升高。所有患者均接受非药物治疗，大多数需要药物治疗。COVID-19 后 6 到 8 个月，17 (85%) 名患者有残留的自主神经症状，12 (60%) 名患者无法重返工作岗位。结论 POTS 可以在既往健康的患者中追踪 COVID-19。需要适当的诊断调查和治疗来识别和治疗 COVID-19 后的自主神经功能障碍。