Trait self-control (TSC), defined as the capacity to alter predominant response to promote desirable long-term goals, has been found to facilitate emotional well-being (EWB). However, the neural correlates underlying this association remain unclear. The present study estimated resting-state brain activity and connectivity with amplitude of low-frequency fluctuations (ALFFs) and resting-state functional connectivity (rsFC) among late adolescents. Whole-brain correlation analysis showed that higher TSC was associated with increased ALFFs in regions within the executive control network (inferior frontal gyrus, IFG) and the salience network (anterior insula, AI) and decreased ALFF in regions (e.g. medial frontal gyrus, MFG; posterior cingulate, PC) within the default-mode network (DMN). TSC was also linked with the integration (e.g. increased IFG-PC connectivity) and segregation (e.g. decreased AI-MFG connectivity) among brain networks. Mediation analysis indicated that TSC totally mediated the links from the IFG and the precuneus, FC of the AI and regions of the DMN (e.g. bilateral PC and MFG), to EWB. Additionally, ALFF in the IFG and the MFG could predict negative affect in the pandemic through TSC. These findings suggest that TSC is involved in several regions and functional organizations within and between brain networks and mediated the association between neural correlates and emotional wellness in adolescence.

中文翻译：

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特质自我控制介导静息态神经相关因素与青春期后期情绪健康之间的关联


特质自我控制（TSC）被定义为改变主要反应以促进理想的长期目标的能力，被发现可以促进情绪健康（EWB）。然而，这种关联背后的神经相关性仍不清楚。本研究评估了青少年晚期静息态大脑活动和低频波动幅度（ALFF）的连通性以及静息态功能连通性（rsFC）。全脑相关分析表明，较高的 TSC 与执行控制网络（额下回，IFG）和显着网络（前岛叶，AI）内区域的 ALFF 增加以及区域（例如内侧额回，MFG）的 ALFF 减少相关。 ；默认模式网络（DMN）内的后扣带回（PC）。 TSC 还与大脑网络之间的整合（例如增加的 IFG-PC 连接性）和分离（例如减少的 AI-MFG 连接性）有关。中介分析表明，TSC 完全介导了从 IFG 和楔前叶、AI 的 FC 和 DMN 区域（例如双侧 PC 和 MFG）到 EWB 的联系。此外，IFG 和 MFG 中的 ALFF 可以通过 TSC 预测大流行的负面影响。这些发现表明，TSC 参与大脑网络内部和之间的多个区域和功能组织，并介导神经相关因素与青春期情绪健康之间的关联。