Purpose Understanding how religion and spirituality influence health-related quality of life (HRQoL) is important for developing holistic, patient-centered treatment. This study determined distinct latent classes of religiousness/spirituality for adult persons living with HIV (PLWH) and associations between latent class membership and HRQoL. Methods Baseline data was collected from 223 patients in the FAmily CEntered (FACE) Advance Care Planning (ACP) clinical trial for PLWH. Patients completed the Brief Multidimensional Measurement of Religiousness/Spirituality (BMMRS-adapted), Patient Health Questionnaire (PHQ-9), Medical Outcome Study-HIV Survey (MOS-HIV) and the Palliative care Outcome Scale (POS). The optimal number of latent classes was determined by comparing K-Class model with (K-1)-Class model iteratively. The relationship between latent class membership, HRQoL and demographic characteristics was assessed. Results Patients were 56.1% male, 86.1% Black/African American, aged 22-77 (Mean=50.83). 75.3% were Christian. LCA identified three classes: traditionally religious (35%), privately religious (47.1%), and spiritual but not religious (17.9%). MOS-HIV mental health (p < 0.001), MOS-HIV quality of life (p = 0.014) and MOS-HIV health transition (p = 0.016) scores were significantly higher among patients who were traditionally religious. These patients were more likely to be 40+ years and Black. Patients in the privately religious group had the lowest levels of mental health and HRQoL. Conclusions Understanding how religiousness and spirituality influence HRQoL can help the medical community develop holistic, patient-centered and culturally-sensitive interventions that could improve outcomes for PLWH and potentially mitigate the impact of health disparities within the Black and LGBTQ communities.

中文翻译：

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宗教和灵性在艾滋病毒携带者健康相关的生活质量中的作用：潜在类别分析。

目的了解宗教和灵性如何影响与健康相关的生活质量（HRQoL）对于开发以患者为中心的整体治疗很重要。这项研究确定了成人艾滋病毒感染者（PLWH）的宗教/精神信仰的不同潜在类别，以及潜在类别成员与HRQoL之间的关联。方法在FAmily CEntered（FACE）预先护理计划（ACP）的PLWH临床试验中收集了223例患者的基线数据。患者完成了宗教/精神倾向的简短多维测量（适应BMMRS），患者健康调查表（PH​​Q-9），医学成果研究-HIV调查（MOS-HIV）和姑息治疗成果量表（POS）。通过迭代比较K-Class模型和（K-1）-Class模型，确定潜在类别的最佳数量。评估了潜在的班级成员，HRQoL和人口统计学特征之间的关系。结果患者为56.1％的男性，86.1％的黑人/非裔美国人，年龄在22-77岁（平均= 50.83）。75.3％是基督徒。LCA确定了三类：传统宗教（35％），私人宗教（47.1％）和精神而非宗教（17.9％）。在传统宗教信仰的患者中，MOS-HIV的心理健康（p <0.001），MOS-HIV的生活质量（p = 0.014）和MOS-HIV的健康过渡（p = 0.016）得分显着更高。这些患者更有可能是40岁以上的黑人。私人宗教团体中的患者心理健康和HRQoL最低。结论了解宗教和灵性如何影响HRQoL可以帮助医学界发展整体，