We demonstrate cell-substrate interaction on aluminium oxide thin-film in metal-insulator-metal structure followed by the change in dielectric characteristics of Al ₂ O ₃ as a function of progression of cellular growth. The theoretical calculation of the fabricated biosensor reveals that the changes in the intrinsic elemental parameters are mainly attributed to the cell-induced behavioural changes.

中文翻译：

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基于氧化铝薄膜的体外细胞基质传感装置，用于监测成肌细胞的增殖

我们证明了金属-绝缘体-金属结构中氧化铝薄膜上的细胞-基材相互作用，随后 Al ₂ O _{3 的}介电特性 随细胞生长的进程而变化。制造的生物传感器的理论计算表明，内在元素参数的变化主要归因于细胞诱导的行为变化。