We demonstrate cell-substrate interaction on aluminium oxide thin-film in metal-insulator-metal structure followed by the change in dielectric characteristics of Al2O3 as a function of progression of cellular growth. The theoretical calculation of the fabricated biosensor reveals that the changes in the intrinsic elemental parameters are mainly attributed to the cell-induced behavioural changes.

中文翻译：

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基于氧化铝薄膜的体外细胞底物传感装置，用于监测成肌细胞的增殖。

我们证明了氧化铝-薄膜在金属-绝缘体-金属结构中的细胞-基质相互作用，随后随着细胞生长的进展，Al2O3的介电特性发生了变化。制成的生物传感器的理论计算表明，固有元素参数的变化主要归因于细胞诱导的行为变化。