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Mode of delivery of women with Swyer syndrome in a German case series
Journal of Perinatal Medicine ( IF 1.7 ) Pub Date : 2021-07-01 , DOI: 10.1515/jpm-2020-0562
Karen Weisshaupt 1 , Wolfgang Henrich 1 , Jörg Neymeyer 2 , Alexander Weichert 1
Affiliation  

Objectives For women with Swyer Syndrome, a 46,XY gonadal dysgenesis, full term pregnancies are possible after oocyte donation. According to literature, mode of delivery is almost always by Caesarean section for various reasons. Medical indications are multiple pregnancies and related complications, preeclampsia, an androgynous shaped pelvis and failed induction of labor. Elective Caesarean sections were performed based on maternal request and medical recommendation. Methods Following careful examination and shared decision making, we planned a spontaneous delivery with a patient with Swyer syndrome and tested the different hypotheses regarding anatomical and functional features according to literature. In addition, deliveries of women with Swyer Syndrome were analyzed in a German multicenter case series. Results A total of seven women with Swyer syndrome with a total of 10 pregnancies were identified, who later gave birth to twelve live-born children. Seven out of 10 births were performed by elective and non-elective Caesarean section, three births took place vaginally. Conclusions In summary, the risk of Caesarean section delivery has increased, but spontaneous delivery can be attempted in the event of inconspicuous findings.

中文翻译:


德国病例系列中患有 Swyer 综合征的妇女的分娩方式



目标 对于患有 Swyer 综合征(46,XY 性腺发育不全)的女性,卵母细胞捐赠后有可能足月妊娠。根据文献报道,由于各种原因,分娩方式几乎都是剖腹产。医学适应症包括多胎妊娠和相关并发症、先兆子痫、雌雄同体的骨盆和引产失败。根据产妇的要求和医疗建议进行选择性剖腹产。方法 经过仔细检查和共同决策,我们计划对一名 Swyer 综合征患者进行自然分娩,并根据文献测试有关解剖和功能特征的不同假设。此外,在德国多中心病例系列中对患有斯维尔综合症的妇女的分娩进行了分析。结果 共有 7 名患有 Swyer 综合征的女性被鉴定出,她们总共怀孕了 10 次,后来生下了 12 名活产婴儿。十分之七的分娩是通过选择性和非选择性剖腹产进行的,其中三例是顺产。结论 综上所述,剖腹产风险有所增加,但如果发现不明显的情况,可以尝试自然分娩。
更新日期:2021-07-12
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