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Mode of delivery of women with Swyer syndrome in a German case series
Journal of Perinatal Medicine ( IF 2.4 ) Pub Date : 2021-07-01 , DOI: 10.1515/jpm-2020-0562
Karen Weisshaupt 1 , Wolfgang Henrich 1 , Jörg Neymeyer 2 , Alexander Weichert 1
Affiliation  

Objectives For women with Swyer Syndrome, a 46,XY gonadal dysgenesis, full term pregnancies are possible after oocyte donation. According to literature, mode of delivery is almost always by Caesarean section for various reasons. Medical indications are multiple pregnancies and related complications, preeclampsia, an androgynous shaped pelvis and failed induction of labor. Elective Caesarean sections were performed based on maternal request and medical recommendation. Methods Following careful examination and shared decision making, we planned a spontaneous delivery with a patient with Swyer syndrome and tested the different hypotheses regarding anatomical and functional features according to literature. In addition, deliveries of women with Swyer Syndrome were analyzed in a German multicenter case series. Results A total of seven women with Swyer syndrome with a total of 10 pregnancies were identified, who later gave birth to twelve live-born children. Seven out of 10 births were performed by elective and non-elective Caesarean section, three births took place vaginally. Conclusions In summary, the risk of Caesarean section delivery has increased, but spontaneous delivery can be attempted in the event of inconspicuous findings.

中文翻译:

德国病例系列中 Swyer 综合征女性的分娩方式

目标 对于患有 Swyer 综合征(46,XY 性腺发育不全)的女性,在捐卵后有可能足月怀孕。根据文献,由于各种原因,分娩方式几乎总是剖腹产。医学适应症是多胎妊娠和相关并发症、先兆子痫、雌雄同体的骨盆和引产失败。根据产妇的要求和医疗建议进行选择性剖腹产。方法 经过仔细检查和共同决策,我们计划对一名 Swyer 综合征患者进行自然分娩,并根据文献测试有关解剖和功能特征的不同假设。此外,在德国多中心病例系列中分析了患有 Swyer 综合征的妇女的分娩情况。结果共鉴定出 7 名患有 Swyer 综合征的妇女,共怀孕 10 次,后来生下了 12 名活产儿。10 个分娩中有 7 个是通过选择性和非选择性剖腹产进行的,其中 3 个是阴道分娩。结论 总之,剖腹产的风险增加了,但如果发现不明显,可以尝试自然分娩。
更新日期:2021-07-12
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