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CoronaPep: An Anti-Coronavirus Peptide Generation Tool
IEEE/ACM Transactions on Computational Biology and Bioinformatics ( IF 3.6 ) Pub Date : 2021-03-09 , DOI: 10.1109/tcbb.2021.3064630
Aman Chandra Kaushik , Aamir Mehmood , Gurudeeban Selvaraj , Xiaofeng Dai , Yi Pan , Dongqing Wei

The novel coronavirus (COVID-19) infections have adopted the shape of a global pandemic now, demanding an urgent vaccine design. The current work reports contriving an anti-coronavirus peptide scanner tool to discern anti-coronavirus targets in the embodiment of peptides. The proffered CoronaPep tool features the fast fingerprinting of the anti-coronavirus target serving supreme prominence in the current bioinformatics research. The anti-coronavirus target protein sequences reported from the current outbreak are scanned against the anti-coronavirus target data-sets via CORONAPEP which provides precision-based anti-coronavirus peptides. This tool is specifically for the coronavirus data, which can predict peptides from the whole genome, or a gene or protein's list. Besides it is relatively fast, accurate, userfriendly and can generate maximum output from the limited information. The availability of tools like CORONAPEP will immeasurably perquisite researchers in the discipline of oncology and structure-based drug design.

中文翻译:

CoronaPep:一种抗冠状病毒肽生成工具

新型冠状病毒 (COVID-19) 感染现已呈现全球大流行的形式,需要紧急设计疫苗。目前的工作报告设计了一种抗冠状病毒肽扫描工具来识别肽实施例中的抗冠状病毒目标。所提供的 CoronaPep 工具具有抗冠状病毒目标的快速指纹识别功能,在当前的生物信息学研究中发挥着重要作用。通过提供基于精确度的抗冠状病毒肽的 CORONAPEP,针对抗冠状病毒目标数据集对当前爆发报告的抗冠状病毒靶蛋白序列进行扫描。该工具专门用于冠状病毒数据,它可以从全基因组或基因或蛋白质列表中预测肽。此外,它相对快速、准确,用户友好,可以从有限的信息中产生最大的输出。CORONAPEP 等工具的可用性将为肿瘤学和基于结构的药物设计学科的研究人员提供不可估量的优势。
更新日期:2021-03-09
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