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CoronaPep: An Anti-coronavirus Peptide Generation Tool.
IEEE/ACM Transactions on Computational Biology and Bioinformatics ( IF 3.6 ) Pub Date : 2021-03-09 , DOI: 10.1109/tcbb.2021.3064630
Aman Chandra Kaushik , Aamir Mehmood , Gurudeeban Selvaraj , Xiaofeng Dai , Yi Pan , Dong-Qing Wei

The novel coronavirus (COVID-19) infections have adopted the shape of a global pandemic now, demanding an urgent vaccine design. The current work reports contriving an anti-coronavirus peptide scanner tool to discern anti-coronavirus targets in the embodiment of peptides. The proffered CoronaPep tool features the fast fingerprinting of the anti-coronavirus target serving supreme prominence in the current bioinformatics research. The anti-coronavirus target protein sequences reported from the current outbreak are scanned against the anti-coronavirus target data-sets via CORONAPEP which provides precision-based anti-coronavirus peptides. This tool is specifically for the coronavirus data, which can predict peptides from the whole genome, or a gene or protein's list. Besides it is relatively fast, accurate, userfriendly and can generate maximum output from the limited information. The availability of tools like CORONAPEP will immeasurably perquisite researchers in the discipline of oncology and structure-based drug design.

中文翻译:

CoronaPep:一种抗冠状病毒肽生成工具。

目前,新型冠状病毒(COVID-19)感染已成为全球大流行的形式,需要紧急的疫苗设计。当前的工作报道了设计一种抗冠状病毒肽扫描仪工具来识别肽实施方案中的抗冠状病毒靶标。提供的CoronaPep工具具有抗冠状病毒靶标的快速指纹识别功能,在当前的生物信息学研究中占据了举足轻重的地位。通过提供基于精确的抗冠状病毒肽的CORONAPEP,将当前爆发中报告的抗冠状病毒靶蛋白序列与抗冠状病毒靶数据集进行了扫描。该工具专门用于冠状病毒数据,可以从整个基因组或基因或蛋白质列表中预测肽。除了它相对快速,准确,用户友好,可以从有限的信息中产生最大的输出。像CORONAPEP这样的工具的可用性将在肿瘤学和基于结构的药物设计领域极大地吸引研究人员。
更新日期:2021-03-09
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