Early identification of behavioral risk markers for anxiety is essential to optimize long-term outcomes in children with neurodevelopmental disorders. This study analyzed attentional avoidance and its relation to anxiety and autism spectrum disorder (ASD) symptomatology during social and nonsocial fear conditions in toddlers with fragile X syndrome (FXS) and Down syndrome (DS). Toddlers with FXS and DS exhibited increased nonsocial attentional avoidance relative to typically developing (TD) toddlers. Attentional avoidance was not related to anxiety symptom severity in any group; however, higher ASD symptom severity was related to more social attentional avoidance in the FXS and TD groups. Findings suggest that there may be different underlying mechanisms driving attentional avoidance across neurodevelopmental disorders.

中文翻译：

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患有易碎X综合征和唐氏综合症的幼儿的注意偏见和前驱性焦虑症状。

尽早发现焦虑的行为危险标志物对于优化神经发育障碍儿童的长期预后至关重要。这项研究分析了脆性X综合征（FXS）和唐氏综合征（DS）的幼儿在社交和非社交恐惧状况下的注意回避及其与焦虑和自闭症谱系障碍（ASD）症状的关系。相对于典型的发展中（TD）幼儿，具有FXS和DS的幼儿表现出更高的非社交注意力回避率。注意回避与任何组的焦虑症状严重程度无关。然而，在FXS和TD组中，较高的ASD症状严重程度与避免社交注意有关。研究结果表明，可能存在不同的潜在机制来驱动跨神经发育障碍的注意力回避。