For individuals with a personality disorder (PD), it is unknown whether additional psychiatric conditions increase their risk of self-harm. The authors therefore conducted a retrospective cohort study, using data from secondary mental health care, to identify self-harm admissions. Adults with diagnosed PD, followed up over a 6-year period, were involved (N = 7,475). Cox regression was used to model the risk of self-harm admissions, with comorbid depression, substance use disorders (SUD), severe mental illness (SMI), anorexia nervosa (AN), and bulimia nervosa (BN) as primary exposures; sociodemographics were considered as confounders. In multivariable analyses, comorbid SUD (adjusted HR = 1.66; 95% CI [1.45, 1.90]), depressive disorder (1.25; [1.09, 1.44]), AN (1.63; [1.10, 2.39]), and BN (1.65; [1.09, 2.51]) were positively associated with increased risks of hospitalization due to self-harm. However, a negative association was found for comorbid SMI. The findings highlight the importance of assessing and treating comorbid psychiatric disorders in PD.

中文翻译：

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人格障碍患者因自残而入院第一综合医院的风险：一项回顾性队列研究。

对于患有人格障碍（PD）的人来说，尚不清楚其他精神疾病是否会增加他们自残的风险。因此，作者利用二级心理保健的数据进行了一项回顾性队列研究，以确定自残的情况。被诊断为 PD 的成年人参与了为期 6 年的随访（N = 7,475）。使用 Cox 回归来模拟自残入院的风险，以共病抑郁症、物质使用障碍 (SUD)、严重精神疾病 (SMI)、神经性厌食症 (AN) 和神经性贪食症 (BN) 作为主要暴露；社会人口统计学被认为是混杂因素。在多变量分析中，共病 SUD（调整后 HR = 1.66；95% CI [1.45，1.90]）、抑郁症（1.25；[1.09，1.44]）、AN（1.63；[1.10，2.39]）和 BN（1.65；[1.10，2.39]）。 [1.09, 2.51]）与因自残而住院的风险增加呈正相关。然而，共病 SMI 呈负相关。研究结果强调了评估和治疗帕金森病合并精神疾病的重要性。