For individuals with a personality disorder (PD), it is unknown whether additional psychiatric conditions increase their risk of self-harm. The authors therefore conducted a retrospective cohort study, using data from secondary mental health care, to identify self-harm admissions. Adults with diagnosed PD, followed up over a 6-year period, were involved (N = 7,475). Cox regression was used to model the risk of self-harm admissions, with comorbid depression, substance use disorders (SUD), severe mental illness (SMI), anorexia nervosa (AN), and bulimia nervosa (BN) as primary exposures; sociodemographics were considered as confounders. In multivariable analyses, comorbid SUD (adjusted HR = 1.66; 95% CI [1.45, 1.90]), depressive disorder (1.25; [1.09, 1.44]), AN (1.63; [1.10, 2.39]), and BN (1.65; [1.09, 2.51]) were positively associated with increased risks of hospitalization due to self-harm. However, a negative association was found for comorbid SMI. The findings highlight the importance of assessing and treating comorbid psychiatric disorders in PD.

中文翻译：

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人格障碍患者首次进入综合医院进行自我保健的风险：一项回顾性队列研究。

对于患有人格障碍（PD）的个人，尚不清楚其他精神病是否会增加其自我伤害的风险。因此，作者利用来自二级精神卫生保健的数据进行了一项回顾性队列研究，以识别自我伤害的入院情况。参与了诊断为PD的成年人，并进行了为期6年的随访（N = 7,475）。使用Cox回归来模拟自我伤害的风险，主要包括合并症，抑郁症，物质使用障碍（SUD），严重精神疾病（SMI），神经性厌食症（AN）和神经性贪食症（BN）。社会人口统计学被认为是混杂因素。在多变量分析中，共病SUD（调整后的HR = 1.66； 95％CI [1.45，1.90]），抑郁症（1.25； [1.09、1.44]），AN（1.63； [1.10、2.39]）和BN（1.65; [1.09，2。51]）与自我伤害导致住院风险增加呈正相关。但是，发现并发SMI呈负相关。这些发现凸显了评估和治疗PD合并症的精神疾病的重要性。