A topological descriptor is a mathematical illustration of a molecular construction that relates particular physicochemical properties of primary molecular structure as well as its mathematical depiction. Topological co-indices are usually applied for quantitative structure action relationships (QSAR) and quantitative structure property relationships (QSPR). Topological co-indices are topological descriptor which consider the noncontiguous vertex set. In this study, we studyied some of the accompanied renowned topological co-indices: the 1st and 2nd Zagreb co-indices, the 1st and 2nd multiplicative Zagreb co-indices, and the F-coindex. By applying structure based examinations and deductions, we discuss the earlier stated co-indices of few synthetic atomic structures that are frequently used in clinical, synthetic, and material designing

拓扑描述符是分子结构的数学说明，它涉及一级分子结构的特定物理化学性质及其数学描述。拓扑协指数通常应用于定量结构作用关系（QSAR）和定量结构性质关系（QSPR）。拓扑协索引是考虑非连续顶点集的拓扑描述符。在这项研究中，我们研究了一些伴随的著名拓扑协指数：第 1 和第 2 萨格勒布协指数、第 1 和第 2 乘法萨格勒布协指数和 F 协指数。通过应用基于结构的检查和推论，我们讨论了在临床、合成和材料设计中经常使用的少数合成原子结构的早期联合指数