OBJECTIVE Scalable, efficiently delivered treatments are needed to address the needs of women Veterans with PTSD. This randomized clinical trial compared an online, coach-assisted cognitive behavioral intervention tailored for women Veterans with PTSD to phone monitoring only. METHOD Women Veterans who met diagnostic criteria for PTSD were randomized to an 8-week web-based intervention, called DElivery of Self TRaining and Education for Stressful Situations (DESTRESS)-Women Veterans version (WV), or to phone monitoring only (N = 102). DESTRESS-WV consisted of online sessions and 15-min weekly phone calls from a study coach. Phone monitoring included 15-min weekly phone calls from a study coach to offer general support. PTSD symptom severity (PTSD Symptom-Checklist-Version 5 [PCL-5]) was evaluated pre and posttreatment, and at 3 and 6 months posttreatment. RESULTS More participants completed phone monitoring than DESTRESS-WV (96% vs. 76%, p = 0.01), although treatment satisfaction was significantly greater in the DESTRESS-WV condition. We failed to confirm the superiority of DESTRESS-WV in intent-to-treat slope changes in PTSD symptom severity. Both treatments were associated with significant reductions in PTSD symptom severity over time. However, post hoc analyses of treatment completers and of those with baseline PCL ≥ 33 revealed that the DESTRESS-WV group had greater improvement in PTSD symptom severity relative to phone monitoring with significant differences at the 3-month follow-up assessment. CONCLUSIONS Both DESTRESS-WV and phone monitoring resulted in significant improvements in women Veterans' PTSD symptoms. DESTRESS-WV may be an appropriate care model for women Veterans who can engage in the demands of the treatment and have higher baseline symptoms. Future research should explore characteristics of and the methods of reliably identifying women Veterans who are most likely to benefit. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

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针对女性退伍军人的在线，教练辅助自我管理PTSD干预措施的随机试验。

目的需要可扩展的，有效交付的治疗方法，以解决患有PTSD的女性退伍军人的需求。这项随机临床试验比较了为患有PTSD的女性退伍军人量身定制的在线，教练协助的认知行为干预服务，仅将其用于电话监控。方法将符合PTSD诊断标准的退伍军人随机分为8周的基于网络的干预措施，称为“自我指导和压力情况教育”（DESTRESS）-“退伍军人”女性版（WV），或仅进行电话监控（N = 102）。DESTRESS-WV包括在线课程和每周15分钟的学习教练打来的电话。电话监控包括每周15分钟的研究教练打来的电话，以提供一般支持。在治疗前后评估了PTSD症状的严重程度（PTSD症状清单5 [PCL-5]），在治疗后3个月和6个月。结果尽管在DESTRESS-WV条件下的治疗满意度明显高于DESTRESS-WV，但完成电话监控的参与者多于DESTRESS-WV（96％比76％，p = 0.01）。我们未能证实DESTRESS-WV在PTSD症状严重程度的意向治疗斜率变化方面的优势。随着时间的推移，两种治疗均与PTSD症状严重程度的显着降低有关。但是，对治疗完成者和基线PCL≥33者的事后分析显示，相对于电话监测，DESSTRES-WV组在PTSD症状严重程度方面有更大的改善，在3个月的随访评估中有显着差异。结论DESTRESS-WV和电话监控都可以显着改善女性退伍军人的PTSD症状。DESTRESS-WV可能是适合从事治疗需求并具有较高基线症状的女性退伍军人的合适护理模式。未来的研究应探索最有可能受益的女性退伍军人的特征和方法。（PsycInfo数据库记录（c）2021 APA，保留所有权利）。