This systematic review evaluates single-case research design studies investigating applied behavior analytic (ABA) interventions for people with Down syndrome (DS). One hundred twenty-five studies examining the efficacy of ABA interventions on increasing skills and/or decreasing challenging behaviors met inclusion criteria. The What Works Clearinghouse standards and Risk of Bias in N-of-1 Trials scale were used to analyze methodological characteristics, and Tau-U effect sizes were calculated. Results suggest the use of ABA-based interventions are promising for behavior change in people with DS. Thirty-six high-quality studies were identified and demonstrated a medium overall effect. A range of outcomes was targeted, primarily involving communication and challenging behavior. These outcomes will guide future research on ABA interventions and DS.

中文翻译：

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对唐氏综合症患者应用行为分析干预的单例研究的荟萃分析。

该系统评价评估了单例研究设计研究，该研究研究了唐氏综合症（DS）患者的应用行为分析（ABA）干预措施。一百二十五项检查ABA干预对提高技能和/或减少挑战性行为的功效的研究符合纳入标准。使用What's Clearinghouse标准和N-of-1试验量表中的偏倚风险来分析方法学特征，并计算Tau-U效应量。结果表明，基于ABA的干预措施有望改变DS患者的行为。鉴定了36项高质量研究，这些研究显示了总体中等效果。目标是一系列结果，主要涉及沟通和具有挑战性的行为。这些结果将指导未来有关ABA干预和DS的研究。