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Laryngeal Chemoreflex in Health and Disease: A Review.
Chemical Senses ( IF 2.8 ) Pub Date : 2020-12-05 , DOI: 10.1093/chemse/bjaa069
Shivani Pathak 1 , Laurie Slovarp 2 , Matthew S Clary 1 , Marie E Jetté 1
Affiliation  

The larynx plays a key role in airway protection via the laryngeal chemoreflex (LCR). This involuntary reflex can be evoked when hazardous substances activate mucosal receptors, which send signals to be processed within the brainstem. Although the LCR is meant to be protective, the reflex can become hyperstimulated, even to benign stimuli, which can result in pathological disorders, such as chronic cough and inducible laryngeal obstruction. In this review, we will outline the mechanism of the LCR and its associated pathological disorders.

中文翻译:

健康与疾病中的喉化学反射:综述。

喉部通过喉部化学反射 (LCR) 在气道保护中发挥关键作用。当有害物质激活粘膜受体时,可以诱发这种无意识的反射,粘膜受体发送信号以在脑干内进行处理。尽管 LCR 旨在具有保护作用,但反射可能会过度刺激,甚至是良性刺激,这可能导致病理性疾病,例如慢性咳嗽和诱导性喉梗阻。在这篇综述中,我们将概述 LCR 的机制及其相关的病理障碍。
更新日期:2020-12-05
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