Enzymes are the biocatalysts synthesized by living organisms having high specificity, catalytic activity, and a broad range of applicability. One such biotechnologicaly relevant enzyme is keratinase with various industrial application that captures a significant place in the enzyme market. It belongs to the proteolytic enzyme group that cleaves the highly stable and fibrous protein, keratin through hydrolysis. Keratins are hard- corrupting sinewy proteins insoluble in natural solvents and water. It is frequently aggregated in nature and expressively present in the plumes, hair, nail, horn, skins, feet, etc. The maximum range of microorganisms, such as bacteria, fungi, and actinomycetes have been accounted for producing keratinases with significant biotechnological applications. Successful application of this group of enzymes have been seen in various industries such as farming, laundry detergent, cosmetics, animal feed, pharmaceutical, leather, and textile. Moreover they have found remarkable usability in environmentally friendly waste management also. This paper focuses on the structure, sources, and various applications of this industrially important enzyme.

中文翻译：

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微生物角蛋白酶对角蛋白的生物降解作用，可实现有效的废物管理和有效的工业应用。

酶是由具有高特异性，催化活性和广泛适用性的活生物体合成的生物催化剂。一种与生物技术相关的酶是具有各种工业应用的角蛋白酶，其在酶市场上占有重要地位。它属于蛋白水解酶基团，可通过水解裂解高度稳定的纤维蛋白角蛋白。角蛋白是不溶于天然溶剂和水的坚硬的辛辣蛋白质。它在自然界中经常聚集，并在羽状，头发，指甲，角，皮肤，脚等中表达性存在。微生物（例如细菌，真菌和放线菌）的最大范围已被认为可产生具有重要生物技术应用的角蛋白酶。这组酶的成功应用已在农业，洗衣粉，化妆品，动物饲料，制药，皮革和纺织等各个行业中见到。此外，他们还发现了在环保废物管理方面的卓越可用性。本文重点介绍这种工业上重要的酶的结构，来源和各种应用。