Background: Polymers are used in drug delivery systems to encapsulate and release the drug. Natural polymers have the advantages of biodegradability, biocompatibility, and recognizable biological moieties that maintain cellular functions as compared to synthetic polymers. Chitosan is a natural polycationic linear polysaccharide that originates from chitin. Its easy modification, release rate of drug, ability to cross-link with other polymers, gelling ability, immunostimulation, bioadhesion, biocompatibility, and biodegradability has increased its application in various drug delivery systems.

Objective: The objective of the present study is to overview the recent patents of the application of chitosan in various drug delivery systems and their use in the prevention of cancer and other ailments.

Methods: In this review, the patent application of chitosan in various drug delivery systems employed to cure mainly cancer has been covered with particular emphasis on their scientific impact and novelty.

Results: Chitosan has proved its potential as a polymer to control and target the drug at the site of action.

Conclusion: The potential of chitosan and its derivatives to deliver and target the drug may open new avenues for therapeutic interventions in different tumors.

背景：聚合物用于药物递送系统以封装和释放药物。与合成聚合物相比，天然聚合物具有生物可降解性、生物相容性和可识别的维持细胞功能的生物部分的优点。壳聚糖是一种来源于甲壳素的天然聚阳离子线性多糖。其易修饰性、药物释放率、与其他聚合物的交联能力、胶凝能力、免疫刺激性、生物粘附性、生物相容性和生物降解性增加了其在各种药物递送系统中的应用。

目的：本研究的目的是概述壳聚糖在各种药物输送系统中的应用及其在预防癌症和其他疾病中的应用的最新专利。

方法：在这篇综述中，壳聚糖在用于主要治疗癌症的各种药物递送系统中的专利申请已经涵盖，并特别强调了它们的科学影响和新颖性。

结果：壳聚糖已证明其作为聚合物在作用部位控制和靶向药物的潜力。

结论：壳聚糖及其衍生物递送和靶向药物的潜力可能为不同肿瘤的治疗干预开辟新途径。