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γ-Fe2O3 nanoflowers as efficient magnetic hyperthermia and photothermal agent
Applied Surface Science ( IF 6.7 ) Pub Date : 2021-05-07 , DOI: 10.1016/j.apsusc.2021.150025
S.K. Shaw , J. Kailashiya , A. Gangwar , S.K. Alla , Santosh K. Gupta , C.L. Prajapat , Sher Singh Meena , D. Dash , P. Maiti , N.K. Prasad

Recent reports on the magnetic nanoparticles (MNPs) as an efficient and alternative photothermal agent have excited the researchers worldwide. While MNPs have been explored well for high heating performance during magnetic hyperthermia (MHT), their full potential is yet to be explored as an efficient photothermal agent. In addition, the simultaneous exposure of alternating magnetic field (for MHT) and near infrared irradiation (for photothermal therapy PTT) can drastically enhance the heating behaviour of MNPs. In the present work we explored microwave assisted polyol method to get γ-Fe2O3 nanoflowers. The use of sodium acetate in varying amounts, as an alkali source, allowed the modification of structural and magnetic properties leading to the formation of nanoflower with high heating performance during MHT and PTT. Role of defects in γ-Fe2O3 nanoflowers were investigated using photoluminescence spectroscopy which highlighted distinct role of oxygen vacancies and surface states. The nanoflowers with better crystallinity and relatively higher coercive field performed well during MHT. The observed high intrinsic loss power value of 15.21 ± 0.34 nHm2Kg-as significantly higher than the commercially available ferrofluids and previously reported values for nanoflowers. During PTT, the therapeutic temperature of 42 °C was achieved for the aqueous suspension with a concentration as low as 100 µg/mL which demonstrates the superiority of γ-Fe2O3 nanoflowers as an efficient PTT agent.



中文翻译:

了γ-Fe 2个ö 3纳米花高效磁热疗和光热剂

关于磁性纳米颗粒(MNP)作为一种有效的替代光热剂的最新报道激起了全世界的研究人员的兴趣。尽管人们已经很好地探索了MNP在磁热疗(MHT)期间具有很高的加热性能,但它们作为一种有效的光热剂的潜力还没有得到开发。另外,同时暴露于交变磁场(用于MHT)和近红外辐射(用于光热疗法PTT)可以大大增强MNP的加热行为。在目前的工作我们探讨微波辅助多元醇方法获得了γ-Fe 2 ö 3纳米花。使用不同量的乙酸钠作为碱源,可以改变结构和磁性,从而导致在MHT和PTT过程中形成具有高加热性能的纳米花。在γ-铁的缺陷的作用2个ö 3使用其中强调氧空位和表面状态的不同作用光致发光光谱纳米花进行了调查。在MHT期间,具有较好结晶度和相对较高矫顽场的纳米花表现良好。15.21±0.34 NHM的所观察到的高的固有损耗功率值2公斤-显着高于市售的铁磁流体和先前报道的纳米花的值。PTT,42的治疗过程中温度℃下对水性悬浮液来实现,其浓度低至100μg/ mL的这表明γ-Fe的优越性2 ö 3纳米花作为一种有效的PTT试剂。

更新日期:2021-05-12
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