BACKGROUND:With inherent flexibility, high electroconductivity, excellent thermal conductivity, easy printability and biosafety, Ga-based functional liquid metals (LMs) have been extensively evaluated for biomedical applications. When implanted in the biological environment, the safety of the LMs is a major concern for future application. METHODS:In this study, we conducted several biocompatibility assessments through immersion experiments, in vitro cytotoxicity experiments and in vivo embedding experiments. RESULTS:The results showed that both the Al-assisted self-driven LM and the LM per se own good biocompatibility and retrievable properties when contacted with living organisms for a relatively long period of time. CONCLUSION:This study provides preliminary evidence about the biocompatibility of the functional LM materials, such as LM-based soft machine, which would promote and inspire other research to address other tough biomedical issues.

中文翻译：

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Ga基和Al辅助自驱动液态金属在细胞和动物给药实验中的生物相容性研究

背景：Ga 基功能性液态金属 (LMs) 具有固有的柔韧性、高导电性、优异的导热性、易印刷性和生物安全性，已被广泛评估用于生物医学应用。当植入生物环境中时，LMs 的安全性是未来应用的主要问题。方法：在本研究中，我们通过浸泡实验、体外细胞毒性实验和体内包埋实验进行了多项生物相容性评估。结果：结果表明，铝辅助自驱动 LM 和 LM 本身在与生物体接触较长时间后都具有良好的生物相容性和可回收性。结论：本研究为功能性LM材料的生物相容性提供了初步证据，