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Retriever and Pointer: Software to Evaluate Inbreeding and Genetic Management in Captive Populations
Animals ( IF 3 ) Pub Date : 2021-05-07 , DOI: 10.3390/ani11051332
Jack J. Windig , Ina Hulsegge

The Retriever and Pointer software has been developed for genetic management of (small) captive populations The Retriever program uses as input pedigree data and extracts data on population structure that determine inbreeding rates such as skewness of sire contributions. Levels and rates of inbreeding and kinship and effective population sizes are determined as well. Data on population structure can be used as input for the Pointer program. This program uses stochastic simulation to evaluate a population and provides expected levels and rates of inbreeding and kinship, and optionally allelic diversity. The user can simulate different options for genetic management such as sire restrictions, restrictions on inbreeding levels, mean kinships and breeding circles. Both Retriever and Pointer can analyze populations with subpopulations and different rates of exchange between them. Although originally devised for dogs, the software can be, and has been, used for any captive population including livestock and zoo populations, and a number of examples are provided. The pointer software is also suitable in education where students may generate their own populations and evaluate effects of different population structures and genetic management on genetic diversity. Input is provided via a graphical user interface. The software can be downloaded for free.

中文翻译:

猎犬和指针:评估圈养种群近亲繁殖和遗传管理的软件

已经开发了Retriever和Pointer软件,用于(小型)圈养种群的遗传管理。Retriever程序使用系谱数据作为输入,并提取有关种群结构的数据,这些数据决定了近交率,例如父系贡献的偏度。还确定了近亲和亲属的水平和比率以及有效的种群数量。人口结构数据可用作Pointer程序的输入。该程序使用随机模拟来评估种群,并提供预期的近交和亲缘关系水平和比率,以及可选的等位基因多样性。用户可以模拟不同的遗传管理选项,例如父亲限制,近交限制,平均血统和繁殖圈。Retriever和Pointer都可以分析具有亚种群以及它们之间的交换速率不同的种群。尽管最初是为狗设计的,但是该软件可以并且已经被用于包括牲畜和动物园种群在内的任何圈养种群,并且提供了许多示例。该指针软件还适用于学生可以产生自己的种群并评估不同种群结构和遗传管理对遗传多样性的影响的教育。输入是通过图形用户界面提供的。该软件可以免费下载。该指针软件还适用于学生可以产生自己的种群并评估不同种群结构和遗传管理对遗传多样性的影响的教育。输入是通过图形用户界面提供的。该软件可以免费下载。该指针软件还适用于学生可以产生自己的种群并评估不同种群结构和遗传管理对遗传多样性的影响的教育。输入是通过图形用户界面提供的。该软件可以免费下载。
更新日期:2021-05-07
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