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Translational Control of Immune Evasion in Cancer
Trends in Cancer ( IF 14.3 ) Pub Date : 2021-05-07 , DOI: 10.1016/j.trecan.2021.04.002
Shruthy Suresh 1 , Kathryn A O'Donnell 2
Affiliation  

Mechanisms that control translation play important roles in tumor progression and metastasis. Emerging evidence has revealed that dysregulated translation also impacts immune evasion in response to cellular or oncogenic stress. Here, we summarize current knowledge regarding the translational control of immune checkpoints and implications for cancer immunotherapies.



中文翻译:


癌症免疫逃避的转化控制



控制翻译的机制在肿瘤进展和转移中发挥着重要作用。新的证据表明,翻译失调也会影响针对细胞或致癌应激的免疫逃避。在这里,我们总结了有关免疫检查点翻译控制及其对癌症免疫疗法的影响的当前知识。

更新日期:2021-06-15
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