Background:It is unclear whether balloon size can influence lesion formation. The aim of this study was to evaluate the impact of balloon size on lesion formation during laser balloon procedures in an in vitro model.

Methods and Results:Laser energy was applied to chicken muscle using a first generation laser balloon. Laser ablation was performed with 2 different balloon sizes (18 mm and 32 mm) using 2 different power settings (12 W/20 s and 8.5 W/20 s) on the chicken muscle. The lesion characteristics, including maximum lesion depth, maximum lesion diameter, surface diameter and depth at maximum diameter, were compared between the 18-mm and 32-mm balloon groups at 12 W/20 s and 8.5 W/20 s, respectively. We created 40 lesions using laser energy at 12 W/20 s and 80 lesions at 8.5 W/20 s. At both power settings, the maximum lesion depth and the depth at the maximum diameter were larger in the 18-mm than in the 32-mm balloon group. At both power settings, the maximum lesion diameter and the surface diameter were smaller in the 18-mm than in the 32-mm balloon group.

Conclusions:The balloon size could affect the lesion formation during laser balloon ablation. The lesion with the larger balloon size was wider and shallower than the lesion with the smaller balloon size.

背景：目前尚不清楚球囊大小是否会影响病变形成。本研究的目的是在体外模型中评估球囊尺寸对激光球囊手术过程中病变形成的影响。

方法和结果：使用第一代激光气球将激光能量应用于鸡肌肉。在鸡肌肉上使用 2 种不同的功率设置（12 W/20 秒和 8.5 W/20 秒）对 2 种不同的气球尺寸（18 毫米和 32 毫米）进行激光消融。分别在 12 W/20 s 和 8.5 W/20 s 下比较了 18 mm 和 32 mm 球囊组的病变特征，包括最大病变深度、最大病变直径、表面直径和最大直径深度。我们使用 12 W/20 s 的激光能量创建了 40 个病灶，并在 8.5 W/20 s 下创建了 80 个病灶。在两种功率设置下，18-mm 球囊组的最大损伤深度和最大直径处的深度大于 32-mm 球囊组。在两种功率设置下，18-mm 球囊组的最大病变直径和表面直径小于 32-mm 球囊组。

结论：球囊尺寸会影响激光球囊消融术中的病灶形成。球囊尺寸较大的病灶比球囊尺寸较小的病灶更宽、更浅。