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Effect of Aegle marmelos on the growth of brushite crystals
Clinical Phytoscience Pub Date : 2021-05-07 , DOI: 10.1186/s40816-021-00280-6
G. Anushya , R. Mahesh , T. H. Freeda , R. Ramachandran , G. Raju

The urinary stone formation is a very common health problem due to the prolonged medication. Calcium Hydrogen Phosphate Dihydrate (CaHPO4.2H2O, CHPD and Brushite) is one of the major constituent of urinary stone crystals. The formation and deposition of brushite crystals is the central cause of recurrent kidney stone disease among the global population. The present study aims to investigate the effect of Aegle marmelos leaves on the growth of brushite crystals to explicate the inhibitory effect of urinary stones from a different point of view. The CHPD crystals were grown by the Single Diffusion Gel growth technique. In order to inhibit the formation of urinary stones, CHPD crystals are grown in the laboratory in the pure form and by adding the prolonged medicine A. marmelos taken especially by diabetic patients. A comparative study of the pure and A. marmelos leaves added crystals has been carried out using the Growth factor, Powder X-ray diffraction, Microstructural parameters, FTIR and SEM-EDAX. Total mass of the grown crystals is found to decrease with increasing concentrations of leaf extract of the A. marmelos. On comparing with undoped, crystalline size of the A. marmelos doped samples is reduced. Disappearance of absorption band and peak shift in the FTIR shows the incorporation of functional groups of A. marmelos. The morphology changes of the treated crystals are assessed in SEM. The result shows that herbal extracts prepared from A. marmelos have good inhibitory effect on the growth of the brushite urinary stone crystals considered.

中文翻译:

影响木橘对钙磷晶体生长

由于长期用药,尿结石的形成是一个非常普遍的健康问题。二水合磷酸氢钙(CaHPO4.2H2O,CHPD和透钙磷石)是尿石晶体的主要成分之一。透钙磷石晶体的形成和沉积是全球人群肾结石病反复发作的主要原因。本研究的目的是从不同的角度研究马格勒枫叶对透钙铁矿晶体生长的影响,以阐明尿路结石的抑制作用。CHPD晶体通过单扩散凝胶生长技术生长。为了抑制尿结石的形成,CHPD晶体在实验室中以纯净的形式生长,并通过添加特别是糖尿病患者服用的延长药物A. marmelos来生长。使用生长因子,粉末X射线衍射,显微结构参数,FTIR和SEM-EDAX对纯和A. marmelos叶片添加的晶体进行了比较研究。发现生长的晶体的总质量随着A. marmelos叶片提取物浓度的增加而降低。与未掺杂相比,A.marmelos掺杂样品的晶体尺寸减小了。FTIR中吸收带的消失和峰移表明了A. marmelos官能团的结合。在SEM中评估了处理过的晶体的形态变化。结果表明,从A. marmelos制备的草药提取物对所考虑的透钙磷石尿石晶体的生长具有良好的抑制作用。显微结构参数,FTIR和SEM-EDAX。发现生长的晶体的总质量随着A. marmelos叶片提取物浓度的增加而降低。与未掺杂相比,A.marmelos掺杂样品的晶体尺寸减小了。FTIR中吸收带的消失和峰移表明了A. marmelos官能团的结合。在SEM中评估了处理过的晶体的形态变化。结果表明,从A. marmelos制备的草药提取物对所考虑的透钙磷石尿石晶体的生长具有良好的抑制作用。显微结构参数,FTIR和SEM-EDAX。发现生长的晶体的总质量随着A. marmelos叶片提取物浓度的增加而降低。与未掺杂相比,A.marmelos掺杂样品的晶体尺寸减小了。FTIR中吸收带的消失和峰移表明了A. marmelos官能团的结合。在SEM中评估了处理过的晶体的形态变化。结果表明,从A. marmelos制备的草药提取物对所考虑的透钙磷石尿石晶体的生长具有良好的抑制作用。FTIR中吸收带的消失和峰移表明了A. marmelos官能团的结合。在SEM中评估了处理过的晶体的形态变化。结果表明,从A. marmelos制备的草药提取物对所考虑的透钙磷石尿石晶体的生长具有良好的抑制作用。FTIR中吸收带的消失和峰移表明了A. marmelos官能团的结合。在SEM中评估了处理过的晶体的形态变化。结果表明,从A. marmelos制备的草药提取物对所考虑的透钙磷石尿石晶体的生长具有良好的抑制作用。
更新日期:2021-05-07
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