Adolescence is a developmental period characterized by remarkable volatility and comorbidity in internalizing disorders. Delineating internalizing symptom change in a manner that accounts for symptoms' shared versus distinctive features is imperative to an understanding of their development. An additional question concerns how vulnerabilities for internalizing disorders relate to development of internalizing symptoms. Cross-sectional and prospective associations between neuroticism and internalizing psychopathology are well-established, yet conclusive evidence on neuroticism's relation to the progression of symptom dimensions relevant to internalizing disorders remains absent. In this investigation, we used latent growth curve modeling to characterize the trajectories of tri-level model internalizing dimensions (General Distress, Anhedonia-Apprehension, Fears, Anxious Arousal, Fears of Specific Stimuli, Social Fears, Narrow Depression, Interoceptive/Agoraphobic Fears) and examined whether a general neuroticism factor predicted their growth. We used anxiety and depressive symptom data spanning 6 years, collected from 606 high school juniors mostly vulnerable for internalizing disorders. We observed a pattern of results that varied by symptom dimension. Only Anhedonia-Apprehension showed a distinct increasing trend, on average. Neuroticism predicted an adverse symptom course for the dimension of General Distress. Our results reinforce the notion that neuroticism confers substantial risk for internalizing symptom maintenance and extend past findings by demonstrating that neuroticism forecasts a poor symptom course for General Distress but not narrower dimensions of internalizing. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

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神经质和年龄较大的青少年的焦虑和抑郁症状的纵向轨迹。

青春期是一个发育阶段，其特征是内化性疾病具有明显的挥发性和合并症。以解释症状的共有特征与独特特征的方式描述内在症状变化，对于理解其发展势在必行。另一个问题涉及内在性疾病的脆弱性如何与内在性症状的发展相关。神经质和内在化的精神病理学之间的横断面和前瞻性关联是公认的，但是仍然没有关于神经质与内在化的疾病相关的症状维度发展关系的确凿证据。在这项调查中，我们使用了潜在增长曲线建模来表征三级模型内部化维度的轨迹（一般遇险，焦虑症，恐惧，焦虑激怒，对特定刺激的恐惧，社交恐惧，狭窄的抑郁症，感受性/厌恶恐惧症，并检查了一般的神经质因素是否能预测其生长。我们使用了6年的焦虑和抑郁症状数据，这些数据来自606位最容易内在化疾病的高中生。我们观察到了随症状维度而变化的结果模式。平均而言，只有对快感的恐惧才显示出明显的增长趋势。神经质主义预言了一般性困扰的不良症状过程。我们的研究结果强化了这样的观点，即神经质症会给症状内在维持提供实质性风险，并通过证明神经质症预示了一般性困扰的不良症状进程而不是狭窄的内因化过程而扩展了以往的发现。（PsycInfo数据库记录（c）2021 APA，保留所有权利）。