Background: The prevention of AIDS among undergraduates in Wuhan is a public health priority. An important strategy for students to prevent AIDS is to establish correct moral concepts and cultivate a healthy lifestyle.

Introduction: Through the investigation of MSM and non-MSM population in college students, this study seeks for possible influencing factors and solutions for AIDS prevention in colleges and universities.

Methods: This study was carried out in 15 universities in Wuhan. We recruited 127 MSM students through peer promotion, and 510 non-MSM students were selected by random cluster sampling. The two groups were investigated by anonymous questionnaire, and the questionnaire information was statistically analyzed.

Results: The awareness rate of AIDS-related knowledge among MSM students was 90.8%, while that among non-MSM students, it was 64.6%; neither meets the national requirements. The self- -recognition of MSM undergraduates was 95.0%. Among the 497 non-MSM undergraduates, 65.4% were willing to make friends with the MSM undergraduates. There were statistical differences in the social discrimination attitudes of those who knew AIDS-related knowledge (P<0.01), and the attitudes of those with knowledge of AIDS were more positive.

Conclusion: The MSM students reported a high incidence of high-risk sexual behaviors and a gap between knowledge and behaviors. This study focuses on the comparison of the characteristics of knowledge, attitude, and behavior on AIDS between the two groups of people. AIDS prevention in colleges and universities requires a new way of thinking.

背景：武汉市大学生艾滋病防治工作是公共卫生的重点。学生预防艾滋病的一个重要策略是树立正确的道德观念，养成健康的生活方式。

引言：本研究通过对大学生MSM和非MSM人群的调查，寻找高校艾滋病预防工作的可能影响因素及解决方案。

方法：本研究在武汉市15所高校进行。我们通过同伴晋升招募了 127 名 MSM 学生，并通过随机整群抽样选择了 510 名非 MSM 学生。对两组进行匿名问卷调查，并对问卷信息进行统计分析。

结果：MSM学生艾滋病相关知识知晓率为90.8%，非MSM学生为64.6%；都不符合国家要求。MSM本科生自我认同率为95.0%。在497名非MSM本科生中，65.4%愿意与MSM本科生交朋友。了解艾滋病相关知识者的社会歧视态度差异有统计学意义（P<0.01），且了解艾滋病者的态度更积极。

结论：MSM 学生报告了高危性行为的高发生率以及知识与行为之间的差距。本研究重点比较两组人群对艾滋病的知识、态度和行为特征。高校艾滋病防治需要一种新的思维方式。