A novel method based on fabric phase sorptive extraction (FPSE) followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) has been validated for the simultaneous determination of 11 UV filters (ethylhexyl salicylate, benzyl salicylate, homosalate, benzophenone-3, isoamylmethoxycinnamate, 4-methylbenzylidenecamphor, methyl anthranilate, etocrylene, 2-ethylhexylmethoxycinnamate, 2-ethylhexyl p-dimethylaminobenzoate, and octocrylene), in natural and recreational waters. Major experimental parameters affecting FPSE procedure have been optimized to obtain the highest extraction efficiency. Different types and sizes of sol-gel coated FPSE media, sample volume, extraction time, and type and volume of desorption solvent were evaluated. The optimal conditions involved the use of a (2.0 × 2.5) cm2 FPSE device with PDMS based coating for the extraction of 20 mL of water for 20 min. The quantitative desorption of the target compounds was performed with 0.5–1 mL of ethyl acetate. The method was satisfactorily validated in terms of linearity, precision, repeatability and reproducibility. Recovery studies were performed at different concentration levels in real water matrices to show its suitability, obtaining mean values about 90% and satisfactory precision. LODs were at the low ng L−1 in all cases. Finally, the validated FPSE-GC-MS/MS method was applied to different real samples, including environmental water (lake, river, seawater) and recreational water (swimming-pool), where 8 out of the 11 studied compounds were detected at concentrations between 0.12-123 μg L−1. FPSE is proposed as an efficient and simple alternative to other extraction and microextraction techniques for the analysis of UV filters in waters. Since no matrix effects were observed, quantification could be carried out by conventional calibration with standard solutions, without the need to perform the complete FPSE procedure, thus allowing a higher throughput in comparison with other microextraction techniques.

中文翻译：

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开发一种基于织物相吸附萃取和气相色谱-串联质谱法的分析方法，以确定环境和娱乐水域中的紫外线过滤剂

一种基于织物相吸附萃取 (FPSE) 和气相色谱-串联质谱 (GC-MS/MS) 的新方法已被验证可同时测定 11 种紫外线过滤剂（水杨酸乙基己酯、水杨酸苄酯、高水杨酸、二苯甲酮 3 、异戊基甲氧基肉桂酸酯、4-甲基亚苄基樟脑、邻氨基苯甲酸甲酯、依托克林、2-乙基己基甲氧基肉桂酸酯、2-乙基己基对二甲氨基苯甲酸酯和奥克立林），在天然和娱乐水域中。对影响 FPSE 程序的主要实验参数进行了优化，以获得最高的提取效率。评估了不同类型和尺寸的溶胶-凝胶涂层 FPSE 介质、样品体积、提取时间以及解吸溶剂的类型和体积。最佳条件涉及使用 (2.0 × 2. 5) 带有 PDMS 涂层的 cm2 FPSE 设备，用于提取 20 mL 水 20 分钟。目标化合物的定量解吸用 0.5–1 mL 乙酸乙酯进行。该方法在线性、精密度、重复性和再现性方面得到了令人满意的验证。在真实水基质中以不同浓度水平进行回收率研究以显示其适用性，获得约 90% 的平均值和令人满意的精度。在所有情况下，LOD 均处于低 ng L-1。最后，将经过验证的 FPSE-GC-MS/MS 方法应用于不同的实际样品，包括环境水（湖泊、河流、海水）和娱乐用水（游泳池），其中 11 种研究化合物中有 8 种在浓度下检测到在 0.12-123 μg L-1 之间。FPSE 被提议作为其他提取和微提取技术的有效且简单的替代方法，用于分析水中的紫外线过滤剂。由于未观察到基质效应，因此可以通过使用标准溶液的常规校准进行量化，无需执行完整的 FPSE 程序，因此与其他微萃取技术相比具有更高的通量。