Studies investigating the impact of depressive symptoms on obsessive-compulsive disorder (OCD) treatment have yielded mixed findings. The purpose of the study is to extend previous research, which primarily used outpatient samples, to determine whether depression affects OCD treatment outcome among patients receiving intensive residential treatment. OCD patients receiving residential treatment based primarily on exposure and response prevention (ERP) provided data regarding symptoms of depression and OCD at admission and discharge. Patients reported large and significant reductions in OCD symptoms over the course of treatment. Change in OCD symptoms was not significantly affected by depressive symptoms, including patients with severe depressive symptoms. Change in depressive symptoms over the course of treatment was, however, robustly related to change in OCD symptoms, especially among patients who began treatment with severe symptoms of depression. These findings suggest that cognitive-behavior therapy delivered in a residential treatment setting drastically reduces OCD symptoms regardless of depressive symptoms.

中文翻译：

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抑郁症对住宅样本中强迫症治疗的影响。

调查抑郁症状对强迫症 (OCD) 治疗影响的研究得出了不同的结果。该研究的目的是扩展先前主要使用门诊样本的研究，以确定抑郁症是否影响接受强化住院治疗的患者的强迫症治疗结果。主要基于暴露和反应预防 (ERP) 接受住院治疗的强迫症患者提供了有关入院和出院时抑郁症和强迫症症状的数据。患者报告在治疗过程中强迫症症状大幅减少。强迫症症状的变化不受抑郁症状的显着影响，包括患有严重抑郁症状的患者。然而，治疗过程中抑郁症状的变化是 与强迫症症状的变化密切相关，尤其是在开始治疗时出现严重抑郁症状的患者中。这些研究结果表明，无论抑郁症状如何，在住宅治疗环境中进行的认知行为疗法都可以显着减少强迫症症状。