Journal of the International Neuropsychological Society ( IF 2.6 ) Pub Date : 2021-05-06 , DOI: 10.1017/s1355617721000527 Nikki A Lammers 1, 2 , Selma Lugtmeijer 1, 3 , Edward H F de Haan 1 , Roy P C Kessels 3, 4, 5
Deficits in episodic memory are frequently reported after ischemic stroke. In standard clinical care, episodic memory is assessed after a 20–30 min delay, with abnormal memory decay over this period being characterized as rapid forgetting (RF). Previous studies have shown abnormal forgetting over a prolonged interval (days to weeks) despite normal acquisition, referred to as accelerated long-term forgetting (ALF).
Method:We examined whether ALF is present in stroke patients (N = 91) using immediate testing (T1), testing after a short delay (20–30 min, T2), and testing after a prolonged delay (one week, T3). Based on performance compared to matched controls (N = 85), patients were divided into (1) patients without forgetting, (2) patients with RF between T1 and T2, and (3) patients with ALF at T3. Furthermore, confidence ratings were assessed.
Results:ALF was present in a moderate amount of stroke patients (17%), but ALF was even more prevalent in our stroke sample than RF after a 20–30 min delay (which was found in only 13% of our patients). Patients reported a lower confidence for their responses, independent of their actual performance.
Conclusions:Adding a one-week delayed measurement may potentially assist in identifying patients with memory decrements that may otherwise go undetected.
中文翻译:
加速长期遗忘:长期延迟识别作为中风患者长期记忆和元认知信心不同概况的敏感测量
客观的:
缺血性中风后经常报道情景记忆缺陷。在标准临床护理中,情景记忆在延迟 20-30 分钟后进行评估,在此期间异常的记忆衰退被称为快速遗忘 (RF)。先前的研究表明,尽管习得正常,但在较长时间间隔(数天至数周)内仍会出现异常遗忘,称为加速长期遗忘(ALF)。
我们使用立即测试(T1)、短暂延迟后测试(20-30 分钟,T2)和长时间延迟后测试(1 周,T3)检查中风患者 ( N = 91) 是否存在 ALF。根据与匹配对照( N = 85)相比的表现,将患者分为(1)无遗忘患者,(2)T1和T2之间有RF的患者,以及(3)T3时有ALF的患者。此外,还评估了信心评级。
ALF 存在于中等数量的中风患者中 (17%),但在我们的中风样本中,ALF 在延迟 20-30 分钟后比 RF 更普遍(仅在我们的 13% 的患者中发现)。患者对自己的反应信心较低,与他们的实际表现无关。
增加一周的延迟测量可能有助于识别记忆力减退的患者,否则这些患者可能不会被发现。