当前位置:
X-MOL 学术
›
Trends Neurosci.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Stopping the Clock on Seizures!
Trends in Neurosciences ( IF 14.6 ) Pub Date : 2021-05-06 , DOI: 10.1016/j.tins.2021.04.002 Xiaoqin Fu 1 , Judy S Liu 2 , Peijun Li 1
中文翻译:
停止癫痫发作!
更新日期:2021-05-25
Trends in Neurosciences ( IF 14.6 ) Pub Date : 2021-05-06 , DOI: 10.1016/j.tins.2021.04.002 Xiaoqin Fu 1 , Judy S Liu 2 , Peijun Li 1
Affiliation
A recent paper by Zhang et al. shows that REV-ERBα, a negative regulator of the circadian molecular clock, is pro-convulsant through its action on GABA signaling. The findings support the role of the circadian molecular clock in epilepsy and suggest REV-ERBα as a potential therapeutic target for the management of seizures.
中文翻译:
停止癫痫发作!
张等人最近发表的一篇论文。表明 REV-ERBα 是昼夜节律分子钟的负调节剂,通过其对 GABA 信号的作用而促进惊厥。这些发现支持生物钟分子钟在癫痫中的作用,并建议 REV-ERBα 作为治疗癫痫发作的潜在治疗靶点。