We studied the behaviour of three lipid tear products, commercialised by the same brand, as Langmuir films at the air/liquid interface to simulate the ocular environment. No significant differences were observed in the surface behaviour of two of them disclosing the same composition, but commercialised for different applications. The interaction of several subphases, namely sodium chloride, glucose, albumin and lysozyme present in the natural tear, with the lipid films was assessed at room temperature and the temperature of human tear using surface pressure-area isotherms and elastic modulus plots. There is a notable influence of sodium chloride and the proteins albumin and lysozyme on the surface pressure-area isotherm of the lipid Langmuir films. Albumin shifted this isotherm to lower areas while an opposite shift was caused by lysozyme. These studies could be useful for the formulation of new lipid-containing artificial tears, and for increasing the confidence of the customers in commercial eye care formulations.

我们研究了由同一品牌商业化的三种脂质泪液产品的行为，如空气/液体界面处的朗缪尔薄膜，以模拟眼部环境。它们中的两个公开了相同的组成，但针对不同的应用进行了商业化，在表面行为方面没有观察到显着差异。几个亚相，即天然泪液中存在的氯化钠、葡萄糖、白蛋白和溶菌酶与脂质膜的相互作用在室温和人类泪液温度下使用表面压力面积等温线和弹性模量图进行评估。氯化钠和蛋白质白蛋白和溶菌酶对脂质朗缪尔膜的表面压力-面积等温线有显着影响。白蛋白将该等温线移动到较低区域，而溶菌酶引起相反的移动。