Hippocampal neural stem cells (NSCs) and neurogenesis decline sharply with age, though a small population remains. Two articles in this issue of Cell Stem Cell by Ibrayeva et al. (2021) and Harris et al. (2021) indicate the presence of subpopulations of NSCs whose dynamics of activation and self-renewal change over time and may be key to NSC preservation.

中文翻译：

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未来属于那些为今天做好准备的人

海马神经干细胞（NSCs）和神经发生随着年龄的增长而急剧下降，尽管数量仍然很少。Ibrayeva等人在本期《细胞干细胞》中发表了两篇文章。（2021）和Harris等。（2021）指出了NSC亚群的存在，其激活和自我更新的动力学随时间而变化，这可能是NSC保存的关键。