A highly efficient and selective carbon–carbon double bonds cleavage of styrene compounds involving molecular oxygen was achieved using TBHP as a free radical initiator in diethylene glycol diethyl ether medium. Various styrene compounds, such as phenyl acrylic acids and its esters, 2-substituted 3-phenyl acrylic acids and its esters, chalcones, 4-phenyl-3-buten-2-one and bis(2-phenylvinyl) ketone, 5-benzylidene-1,3-dimethyl-pyrimidine-2,4,6-triones, could be effectively oxidized into the corresponding aryl carbonyl compounds, and the yield was up to 99%. A suitable mechanism was proposed. Gram-level synthesis further illustrated the practicality of our method.

使用TBHP作为二甘醇二乙醚介质中的自由基引发剂，可以高效，选择性地裂解涉及分子氧的苯乙烯化合物的碳-碳双键。各种苯乙烯化合物，例如苯基丙烯酸及其酯，2-取代的3-苯基丙烯酸及其酯，查耳酮，4-苯基-3-丁烯-2-酮和双（2-苯基乙烯基）酮，5-亚苄基-1,3-二甲基-嘧啶-2,4,6-三酮可有效地氧化成相应的芳基羰基化合物，收率可达99％。提出了一种合适的机制。克级合成进一步说明了我们方法的实用性。