Objective

The objective of this study was to evaluate the association between (1) different types of ACEs and migraine, and (2) the number of ACEs and migraine among adolescent mothers in Lima, Peru.

Methods

Our cross-sectional study included 787 adolescent mothers (14- to 18-years of age) in Peru. In-person interviews were conducted postpartum, in hospital, within 2-days of delivery. Nine types of ACEs were assessed, including exposure to three categories of abuse, two categories of neglect, and four categories of household dysfunction. Multivariable logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CI) for the association between ACEs and migraine while adjusting for putative confounders.

Results

Approximately 75% of adolescent mothers reported having experienced at least one type of ACE. Adolescent mothers who reported any childhood abuse had 1.49-fold increased odds of migraine (aOR = 1.49; 95% CI 1.03–2.18) compared to those with no history of childhood abuse. Adolescent mothers who reported experiencing household dysfunction had 1.56-fold increase odds of migraine (aOR = 1.56; 95% CI 1.09–2.24). Compared to participants who reported no ACE, those who experienced four or more ACEs had 3.09-fold (aOR = 3.09; 95% CI 1.80–5.40) increased odds of migraine (ptrend < 0.001).

Conclusion

Exposure to ACEs is highly prevalent in adolescent-aged mothers postpartum and is associated with increased odds of migraine. These findings support the importance of screening for ACEs and migraine among adolescent mothers; and the need for providing culturally appropriate, trauma-informed headache care.

中文翻译：

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秘鲁青少年母亲的不良童年经历与偏头痛之间的关联

客观的

本研究的目的是评估 (1) 不同类型的 ACE 与偏头痛之间的关联，以及 (2) 秘鲁利马青少年母亲中 ACE 与偏头痛的数量。

方法

我们的横断面研究包括秘鲁的 787 名青春期母亲（14 至 18 岁）。在产后 2 天内在医院进行面对面访谈。评估了九种 ACE，包括三类虐待、两类忽视和四类家庭功能障碍。多变量逻辑回归程序用于估计 ACE 与偏头痛之间关联的优势比 (OR) 和 95% 置信区间 (95% CI)，同时调整推定的混杂因素。

结果

大约 75% 的青春期母亲报告至少经历过一种 ACE。与没有童年虐待史的母亲相比，报告任何童年虐待史的青少年母亲偏头痛的几率增加了 1.49 倍（aOR = 1.49；95% CI 1.03-2.18）。报告经历家庭功能障碍的青春期母亲偏头痛的几率增加了 1.56 倍（aOR = 1.56；95% CI 1.09-2.24）。与报告没有 ACE 的参与者相比，经历 4 次或更多 ACE 的参与者偏头痛的几率增加了 3.09 倍（aOR = 3.09；95% CI 1.80-5.40）（p趋势 < 0.001）。

结论

ACEs 暴露在青春期母亲产后非常普遍，并且与偏头痛几率增加有关。这些发现支持在青春期母亲中筛查 ACE 和偏头痛的重要性；以及提供文化上适当的、创伤知情的头痛护理的需要。