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Neutron activation survey on patients following BNCT clinical trials at THOR
Applied Radiation and Isotopes ( IF 1.6 ) Pub Date : 2021-05-06 , DOI: 10.1016/j.apradiso.2021.109747
Chun-Kai Huang, Chien-Tien Liu, Shiang-Huei Jiang

In this work neutron activation surveys on 26 patients of recurrent head and neck cancer following boron neutron capture therapy (BNCT) were performed. By means of qualitative neutron activation analysis (NAA), radioactive nuclides activated from neutron capture reaction within patients were identified. The estimated activities of the corresponding radioactive nuclides were achieved based on several assumptions. Gamma-ray dose rate measurements utilizing a survey meter were taken at three chosen distances, namely, 0 cm, 30 cm and 100 cm away from the irradiated region of patients. The variations of gamma-ray dose rate against time were obtained. An approach to estimating the gamma-ray dose rate resulted from each individual radioactive nuclide is also presented.



中文翻译:

THOR BNCT 临床试验后患者的中子活化调查

在这项工作中,对 26 名接受硼中子俘获疗法 (BNCT) 的复发性头颈癌患者进行了中子活化调查。通过定性中子活化分析(NAA),确定了患者体内由中子俘获反应活化的放射性核素。相应放射性核素的估计活度是基于几个假设实现的。利用测量仪在三个选定的距离进行伽马射线剂量率测量,即距患者照射区域 0 厘米、30 厘米和 100 厘米。得到了伽马射线剂量率随时间的变化。还提出了一种估算每个放射性核素产生的伽马射线剂量率的方法。

更新日期:2021-05-11
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