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Carbonic Anhydrase Inhibition Potential and Some Bioactivities of the Peripherally Tetrasubstituted Cobalt(II), Titanium(IV), Manganese(III) Phthalocyanines
Letters in Drug Design & Discovery ( IF 1.2 ) Pub Date : 2021-03-31 , DOI: 10.2174/1570180817999201009162347 Ayça Aktaş Karaçelik 1 , Murat Küçük 2 , Derya Efe 3 , Volkan Çakır 4 , Zekeriya Bıyıklıoğlu 2
中文翻译：
四环取代钴（II），钛（IV），锰（III）酞菁的碳酸酐酶抑制潜能和某些生物活性
更新日期：2021-05-05
Letters in Drug Design & Discovery ( IF 1.2 ) Pub Date : 2021-03-31 , DOI: 10.2174/1570180817999201009162347 Ayça Aktaş Karaçelik 1 , Murat Küçük 2 , Derya Efe 3 , Volkan Çakır 4 , Zekeriya Bıyıklıoğlu 2
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Background: Peripherally tetrasubstituted cobalt(II), titanium(IV), manganese(III) phthalocyanines carrying redox-active metal centers were previously synthesized. Metallophthalocyanines (MPcs) exhibited the potential to use in medicinal applications due to biological activities, such as antibacterial, antioxidant and enzyme inhibition.
Objective: This study's aim was to evaluate the previously synthesized metallophthalocyanines in terms of carbonic anhydrase inhibition, antioxidant, and antimicrobial activities.中文翻译：
四环取代钴（II），钛（IV），锰（III）酞菁的碳酸酐酶抑制潜能和某些生物活性
背景：预先合成了带有氧化还原活性金属中心的四取代钴（II），钛（IV），锰（III）酞菁。由于生物活性，例如抗菌，抗氧化剂和酶抑制作用，金属酞菁（MPcs）具有潜在的医学用途。
目的：本研究旨在评估先前合成的金属酞菁的碳酸酐酶抑制作用，抗氧化剂和抗菌活性。
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