Synthesis and Docking Study of Some Bioactive N-(benzo[d]thiazol-2-yl)- 2-(4-((substituted)phenoxy)acetamide on Cyclo-oxygenase-2 Enzyme and In vivo Analgesic Activity Evaluation,Letters in Drug Design & Discovery

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Synthesis and Docking Study of Some Bioactive N-(benzo[d]thiazol-2-yl)- 2-(4-((substituted)phenoxy)acetamide on Cyclo-oxygenase-2 Enzyme and In vivo Analgesic Activity Evaluation
Letters in Drug Design & Discovery ( IF 1.2 ) Pub Date : 2021-03-31 , DOI: 10.2174/1570180817999201022193901
Sumit Kumar ₁ , Arvind Kumar ₁ , Amit Verma ₂ , Arun Kumar Mishra ₁

Affiliation

Background: The benzothiazole and its derivatives reported an extremely crucial duty in the progress of commercially important intermediary molecules, which are wanted for the manufacturing of various pharmacologically active agents.

Introduction: As a necessary element of ongoing examination for the synthesis of new nonsteroidal anti-inflammatory agents (NSAIDs), a number of new benzothiazole derivatives were taken under consideration for the synthesis and were computationally studied along with their biological activity.

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