Purpose of Review

Increasing attention has been paid in recent decades to social determinants of health as a risk factor for disease development and disease severity. While traditionally heart disease, family history, lipid profile, and tobacco use have all been associated with increased risk of neurological disease, numerous studies now show that the influence of poverty may be just as strong a risk factor. This study summarizes the recent literature on poverty as it contributes to neurological disease.

Recent Findings

Children growing up in poverty have increased risk for cognitive deficits and behavioral disorders as reported by Noble et al. (Dev Sci. 9(6):642–54, 2006) and Farah et al. (Brain Res. 1110(1):166–74, 2006) as well as worse outcomes when it comes to epilepsy management and disease course as discussed by Camfield et al. (Epilepsia. 57(11):1826–33, 2016). In adulthood, as the number of social determinants of health increases, the incidence of stroke and severe stroke increases significantly as reported by Reshetnyak et al. (Stroke. 51:2445–53, 2020) as does exposure to neurologically significant infectious diseases and incidence of dementia as reported by Sumilo et al. (Rev Med Virol. 18(2):81–95, 2008) and Zuelsdorff et al. (Alzheimer’s Dement. 6(1):e12039, 2020).

Summary

Social determinants of health including poverty should be considered a risk factor for disease. More attention is needed from clinicians as well as from a public health perspective to address this disparity.

中文翻译：

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贫困的神经系统并发症：作为健康的社会决定因素的贫困与不良神经疾病结果之间的关联

审查目的

近几十年来，作为疾病发展和疾病严重性的危险因素，健康的社会决定因素已受到越来越多的关注。传统上，心脏病，家族史，血脂状况和烟草使用都与神经系统疾病的风险增加有关，但现在许多研究表明，贫穷的影响可能是同样重要的危险因素。这项研究总结了有关贫困的最新文献，因为贫困会加剧神经系统疾病。

最近的发现

根据Noble等人的报道，在贫穷中成长的儿童增加了认知缺陷和行为障碍的风险。（Dev Sci。9（6）：642-54，2006）和Farah等。（Brain Res。1110（1）：166-74，2006），以及癫痫治疗和疾病进程方面的不良结果，正如Camfield等人所讨论的那样。（癫痫症57（11）：1826-33，2016）。在成年期，随着健康的社会决定因素数量的增加，中风和严重中风的发生率显着增加，正如Reshetnyak等人报道的那样。（Stroke。51：2445-53，2020），如Sumilo等人报道的那样，暴露于具有神经学意义的传染病和痴呆症的发病率也是如此。（Rev Med Virol。18（2）：81-95，2008）和Zuelsdorff等。（阿尔茨海默氏症（Alzheimer's Dement。）6（1）：e12039，2020）。

概括

包括贫困在内的健康的社会决定因素应被视为疾病的危险因素。为了解决这种差距，临床医生以及公共卫生都需要更多的关注。