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Differential Heating of Metal Nanostructures at Radio Frequencies
Physical Review Applied ( IF 3.8 ) Pub Date : 2021-05-04 , DOI: 10.1103/physrevapplied.15.054007
Nicholas J Rommelfanger 1, 2 , Zihao Ou 2, 3 , Carl H C Keck 2, 3 , Guosong Hong 2, 3
Affiliation  

Nanoparticles with a strong absorption of incident radio frequency (rf) or microwave irradiation are desirable for remote hyperthermia treatments. While controversy has surrounded the absorption properties of spherical metallic nanoparticles, other geometries, such as prolate and oblate spheroids, have not received sufficient attention for application in hyperthermia therapies. Here, we use the electrostatic approximation to calculate the relative-absorption ratio of metallic nanoparticles in various biological tissues. We consider a broad parameter space, sweeping across frequencies from 1 MHz to 10 GHz, while also tuning the nanoparticle dimensions from spheres to high-aspect-ratio spheroids approximating nanowires and nanodisks. We find that, while spherical metallic nanoparticles do not offer differential heating in tissue, large absorption cross sections can be obtained from long prolate spheroids, while thin oblate spheroids offer minor potential for absorption. Our results suggest that metallic nanowires should be considered for rf- and microwave-based wireless hyperthermia treatments in many tissues going forward.

中文翻译:

射频下金属纳米结构的差热

具有强烈吸收入射射频 (rf) 或微波辐射的纳米粒子对于远程热疗治疗来说是理想的。虽然围绕球形金属纳米粒子的吸收特性存在争议,但其他几何形状,如长圆形和扁球形,在热疗治疗中的应用还没有得到足够的关注。在这里,我们使用静电近似来计算金属纳米粒子在各种生物组织中的相对吸收率。我们考虑了一个广泛的参数空间,扫描频率从 1 MHz 到 10 GHz,同时还将纳米粒子尺寸从球体调整到近似纳米线和纳米盘的高纵横比球体。我们发现,虽然球形金属纳米粒子不会在组织中提供差异加热,长的扁球体可以获得大的吸收横截面,而薄扁球体提供较小的吸收潜力。我们的研究结果表明,金属纳米线应考虑在未来的许多组织中用于基于射频和微波的无线热疗。
更新日期:2021-05-05
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