In article number 2003332 by Joo‐Hyeon Lee, Yan Yan Shery Huang, and co‐workers, a robust organoid engineering method is developed to ‘up‐size’ and ‘shape’ organoids—miniature collections of cells which mimic biological features of an organ. The method, named Multi‐Organoid Patterning and Fusion (MOrPF), is used to assemble scaffold‐free macroscale airway tubes, leading to flowable organoid‐on‐a‐chip, and branching tubular structures. The organoid fusion process is characterised by inter‐organoid surface integration, luminal clearance, and lumina connection.

中文翻译：

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多组织类器官工程：通过多有机体图案形成和融合进行生物组装的宏观尺度，确定形状的管腔气管（高级科学9/2021）

在Joo-Hyeon Lee，Yan Yan Shery Huang和同事的文章2003332中，开发了一种强大的类器官工程方法来“放大”和“成形”类器官-模拟器官生物特征的微型细胞集合。该方法被称为多有机体图案和融合（MOrPF），用于组装无支架的大型气道导管，从而形成可流动的单芯片类器官和分支管状结构。类器官融合过程的特征是生物体之间的表面整合，管腔间隙和管腔连接。