ABSTRACT

Introduction: Acute pancreatitis (AP) is a common gastrointestinal disease with a wide spectrum of severity and morbidity. Developed in 1974, the Ranson score was the first scoring system to prognosticate AP. Over the past decades, while the Ranson score remains widely used, it was identified to have certain limitations, such as having low predictive power. It has also been criticized for its 48-hour requirement for computation of the final score, which has been argued to potentially delay management. With advancements in our understanding of AP, is the Ranson score still relevant as an effective prognostication system for AP?

Areas covered: This review summarizes the available evidence comparing Ranson score with other conventional and novel scoring systems, in terms of prognostic accuracy, benefits, limitations and clinical applicability. It also evaluates the effectiveness of Ranson score with regard to the Revised Atlanta Classification.

Expert opinion: The Ranson score consistently exhibits comparable prognostic accuracy to other newer scoring systems, and the 48-hour timeframe for computing the full Ranson score is an inherent strength, not a weakness. These aspects, coupled with relative ease of use, practicality and universality of the score, advocate for the continued relevance of the Ranson score in modern clinical practice.

摘要

简介：急性胰腺炎（AP）是一种常见的胃肠道疾病，其严重程度和发病率范围很广。Ranson 评分于 1974 年开发，是第一个预测 AP 的评分系统。在过去的几十年里，虽然 Ranson 评分仍然被广泛使用，但它被发现具有某些局限性，例如预测能力低。它也因其计算最终分数的 48 小时要求而受到批评，这被认为可能会延迟管理。随着我们对 AP 理解的进步，Ranson 评分是否仍然与 AP 的有效预测系统相关？

涵盖的领域：本综述总结了将 Ranson 评分与其他传统和新型评分系统在预后准确性、益处、局限性和临床适用性方面进行比较的现有证据。它还评估 Ranson 分数在修订后的亚特兰大分类方面的有效性。

专家意见： Ranson 评分始终表现出与其他较新评分系统相当的预测准确性，并且计算完整 Ranson 评分的 48 小时时间框架是一种内在优势，而不是弱点。这些方面，加上评分的相对易用性、实用性和普遍性，提倡 Ranson 评分在现代临床实践中的持续相关性。