Measuring health-related quality of life in chronic headache: A comparative evaluation of the Chronic Headache Quality of Life Questionnaire and Headache Impact Test (HIT-6),Cephalalgia

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Measuring health-related quality of life in chronic headache: A comparative evaluation of the Chronic Headache Quality of Life Questionnaire and Headache Impact Test (HIT-6)
Cephalalgia ( IF 5.0 ) Pub Date : 2021-05-04 , DOI: 10.1177/03331024211006045
Kirstie L Haywood ₁ , Felix Achana _{2,

3} , Vivien Nichols ₂ , Gemma Pearce ₄ , Barbara Box ₂ , Lynne Muldoon ₂ , Shilpa Patel ₂ , Frances Griffiths ₅ , Kimberly Stewart ₂ , Martin Underwood _{2,

6} , Manjit M Matharu ₇ ,

Affiliation

Objective

To compare the quality and acceptability of a new headache-specific patient-reported measure, the Chronic Headache Quality of Life Questionnaire (CHQLQ) with the six-item Headache Impact Test (HIT-6), in people meeting an epidemiological definition of chronic headaches.

Methods

Participants in the feasibility stage of the Chronic Headache Education and Self-management Study (CHESS) (n = 130) completed measures three times during a 12-week prospective cohort study. Data quality, measurement acceptability, reliability, validity, responsiveness to change, and score interpretation were determined. Semi-structured cognitive interviews explored measurement relevance, acceptability, clarity, and comprehensiveness.

Results

Both measures were well completed with few missing items. The CHQLQ’s inclusion of emotional wellbeing items increased its relevance to participant’s experience of chronic headache. End effects were present at item level only for both measures. Structural assessment supported the three and one-factor solutions of the CHQLQ and HIT-6, respectively. Both the CHQLQ (range 0.87 to 0.94) and HIT-6 (0.90) were internally consistent, with acceptable temporal stability over 2 weeks (CHQLQ range 0.74 to 0.80; HIT-6 0.86). Both measures responded to change in headache-specific health at 12 weeks (CHQLQ smallest detectable change (improvement) range 3 to 5; HIT-6 2.1).

Conclusions

While both measures are structurally valid, internally consistent, temporally stable, and responsive to change, the CHQLQ has greater relevance to the patient experience of chronic headache.

Trial registration number: ISRCTN79708100. Registered 16th December 2015, http://www.isrctn.com/ISRCTN79708100

中文翻译：

衡量慢性头痛的健康相关生活质量：慢性头痛生活质量问卷和头痛影响测试 (HIT-6) 的比较评估

客观的

为了在符合慢性头痛流行病学定义的人群中比较新的头痛特异性患者报告测量方法——慢性头痛生活质量问卷 (CHQLQ) 与六项头痛影响测试 (HIT-6) 的质量和可接受性。

方法

慢性头痛教育和自我管理研究 (CHESS) 可行性阶段的参与者 (n = 130) 在为期 12 周的前瞻性队列研究中完成了 3 次测量。确定了数据质量、测量可接受性、可靠性、有效性、对变化的响应性和分数解释。半结构化认知访谈探讨了测量的相关性、可接受性、清晰度和全面性。

结果

两项措施都完成得很好，几乎没有遗漏的项目。 CHQLQ 纳入情绪健康项目，增加了其与参与者慢性头痛经历的相关性。对于这两种措施，最终效果仅出现在项目级别。结构评估分别支持 CHQLQ 和 HIT-6 的三因素和一因素解决方案。 CHQLQ（范围 0.87 至 0.94）和 HIT-6（0.90）在内部一致，在 2 周内具有可接受的时间稳定性（CHQLQ 范围 0.74 至 0.80；HIT-6 0.86）。这两项措施均对 12 周时头痛特定健康状况的变化做出了反应（CHQLQ 最小可检测变化（改善）范围 3 至 5；HIT-6 2.1）。