To determine whether children and youths with Type 1 diabetes (T1D) have early alterations of the corneal subbasal nerve plexus detectable with in vivo confocal microscopy (IVCM) and to investigate the role of longitudinally measured major risk factors for diabetes complications associated with these alterations.

中文翻译：

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1 型糖尿病儿童和青少年角膜神经改变的体内共聚焦显微镜研究

确定患有 1 型糖尿病 (T1D) 的儿童和青少年是否具有可通过体内共聚焦显微镜 (IVCM) 检测到的角膜基底神经丛的早期改变，并研究纵向测量的与这些改变相关的糖尿病并发症的主要危险因素的作用。