The production and use of the highly addictive stimulant methamphetamine are a serious public health problem in the USA and globally. Because of its increased popularity with recreational drug users, accidental or intentional poisoning incidents in companion animals have become an unavoidable scenario in veterinary medicine. We describe a case of methamphetamine poisoning in a 4-year-old female German Shepherd, with postmortem analytical quantitation of methamphetamine and its metabolite, amphetamine, in bodily tissues and fluids. Many tissues and bodily fluids can be tested to confirm methamphetamine exposure. More importantly, the higher concentrations found in stomach contents and liver, kidney and heart tissues suggest these are the most useful diagnostic specimens for postmortem confirmation of toxicosis in pets, especially in cases in which the source material is not available for testing or in cases with no postmortem evaluation.

中文翻译：

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犬死后组织和体液中甲基苯丙胺和安非他明的定量


高度成瘾的兴奋剂甲基苯丙胺的生产和使用是美国和全球的一个严重的公共卫生问题。由于其越来越受到娱乐性吸毒者的欢迎，伴侣动物的意外或故意中毒事件已成为兽医学中不可避免的情况。我们描述了一只 4 岁雌性德国牧羊犬甲基苯丙胺中毒的案例，对身体组织和体液中的甲基苯丙胺及其代谢物安非他明进行了死后分析定量。可以测试许多组织和体液来确认甲基苯丙胺暴露。更重要的是，在胃内容物以及肝脏、肾脏和心脏组织中发现的较高浓度表明，这些是用于尸检确认宠物中毒的最有用的诊断样本，特别是在源材料无法用于测试或存在以下情况的情况下：没有尸检评估。