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Delayed embolization associated with increased mortality in pelvic fracture with hemodynamic stability at hospital arrival
World Journal of Emergency Surgery ( IF 6.0 ) Pub Date : 2021-05-03 , DOI: 10.1186/s13017-021-00366-z
Makoto Aoki 1, 2 , Toshikazu Abe 3, 4 , Shokei Matsumoto 1 , Shuichi Hagiwara 5 , Daizoh Saitoh 6 , Kiyohiro Oshima 2
Affiliation  

Embolization is widely used for controlling arterial hemorrhage associated with pelvic fracture. However, the effect of a delay in embolization among hemodynamically stable patients at hospital arrival with a pelvic fracture is unknown. Therefore, our aim was to investigate the association between the time to embolization and mortality in hemodynamically stable patients at hospital arrival with a pelvic fracture. A multicenter, retrospective cohort study was undertaken using data from the Japan Trauma Data Bank between 2004 and 2018. Hemodynamically, stable patients with a pelvic fracture who underwent an embolization within 3 h were divided into six groups of 30-min blocks of time until pelvic embolization (0–30, 30–60, 60–90, 90–120, 120–150, and 150–180 min). We compared the adjusted 30-day mortality rate according to time to embolization. We studied 620 hemodynamically stable patients with a pelvic fracture who underwent pelvic embolization within 3 h of hemorrhage. The median age was 68 (48–79) years and 55% were male. The median injury severity score was 26 (18–38). Thirty-day mortality was 8.9% (55/620) and 24-h mortality was 4.2% (26/619). A Cochran–Armitage test showed that a 30-min delay for embolization was associated with increased 30-day (p = 0.0186) and 24-hour (p = 0.033) mortality. Mortality within 0–30 min to embolization was 0%. The adjusted 30-day mortality rate increased with delayed embolization and was up to 17.0% (10.2–23.9) for the 150–180 min group. Delayed embolization was associated with increased mortality in pelvic fracture with hemodynamic stability at hospital arrival. When you decide to embolize pelvic fracture patients, the earlier embolization may be desirable to promote improved survival regardless of hemodynamics.

中文翻译:

延迟栓塞与住院时血流动力学稳定的骨盆骨折死亡率增加相关

栓塞术广泛用于控制与骨盆骨折相关的动脉出血。然而,对于到院时血流动力学稳定的骨盆骨折患者延迟栓塞的影响尚不清楚。因此,我们的目的是调查血流动力学稳定的骨盆骨折患者入院时栓塞时间与死亡率之间的关系。使用 2004 年至 2018 年日本创伤数据库的数据进行了一项多中心、回顾性队列研究。从血液动力学上讲,在 3 小时内接受栓塞的稳定骨盆骨折患者被分为六组,每组 30 分钟,直到骨盆骨折栓塞(0–30、30–60、60–90、90–120、120–150 和 150–180 分钟)。我们根据栓塞时间比较了调整后的 30 天死亡率。我们研究了 620 名血流动力学稳定的骨盆骨折患者,这些患者在出血后 3 小时内接受了骨盆栓塞术。中位年龄为 68 (48-79) 岁,55% 为男性。损伤严重程度的中位数为 26 (18-38)。30 天死亡率为 8.9% (55/620),24 小时死亡率为 4.2% (26/619)。Cochran-Armitage 检验表明,栓塞延迟 30 分钟与 30 天(p = 0.0186)和 24 小时(p = 0.033)死亡率增加有关。栓塞 0-30 分钟内的死亡率为 0%。调整后的 30 天死亡率随着栓塞延迟而增加,150-180 分钟组高达 17.0% (10.2-23.9)。延迟栓塞与入院时血流动力学稳定的骨盆骨折死亡率增加有关。当您决定对骨盆骨折患者进行栓塞时,
更新日期:2021-05-03
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