### Clinical bottom lines A 4-year-old infant comes into allergy clinic with her parents who say that after eating eggs and egg-containing foods she develops a ‘nettle sting’ rash around the mouth. This usually happens within an hour of eating. After an oral food challenge, an egg allergy is diagnosed. At a follow-up appointment, the parents ask you whether this could have somehow have been prevented. You look into whether early dietary introduction of egg would have played a role. In children (population), does early introduction of egg (intervention) compared with later introduction (comparison) prevent the development of egg allergy (outcome)? All searches were all performed on 17 February 2021. Cochrane Library searched: ‘egg allergy prevention’ and ‘early introduction’; 26 results, none relevant. National Institute for Health and Care Excellence evidence searched: ‘egg allergy prevention’; 204 results, none relevant. PubMed searched (“infant*“[Title/Abstract] OR “child*“[Title/Abstract] OR “paediatric”[Title/Abstract]) …

中文翻译：

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早期引入鸡蛋能防止儿童对鸡蛋过敏吗？

### 临床底线 一个 4 岁的婴儿和她的父母一起来到过敏诊所，她的父母说她吃了鸡蛋和含鸡蛋的食物后，嘴周围会出现“荨麻刺”皮疹。这通常发生在进食后的一个小时内。在口服食物挑战后，诊断出鸡蛋过敏。在后续预约中，父母会问您是否可以以某种方式防止这种情况发生。您会研究早期饮食中引入鸡蛋是否会起作用。在儿童（人群）中，早期引入鸡蛋（干预）与较晚引入（比较）相比是否可以防止鸡蛋过敏（结果）的发展？所有检索均在 2021 年 2 月 17 日进行。Cochrane 图书馆检索了：“鸡蛋过敏预防”和“早期介绍”；26 个结果，没有相关性。国家健康与护理卓越研究所搜索的证据：“鸡蛋过敏预防”；204 个结果，没有相关性。PubMed 搜索（“婴儿*“[标题/摘要]或“儿童*”[标题/摘要]或“儿科”[标题/摘要]）……